Contrast nephropathy is associated with increased morbidity and so this study evaluates the possibility of reducing the required necessary volume of contrast  using coronary intravascular ultrasound (IVUS). Patients were randomized to IVUS  guided angioplasty (n = 41) and angiography guided angioplasty (n = 42). IVUS-guided angioplasty requires a smaller volume of contrast (22.9 ± 12.5 ml versus 71.4 ± 35.9 ml, p <0.001). There was a lengthy procedure using IVUS but that did not affect the radiation dose or fluoroscopy time. In patients at high risk of contrast nephropathy IVUS use must be considered.

Pedro Lemos
2013-10-31

Original title: IVUS Guidance During PCI to Reduce Contrast Use. The MOZART randomized trial