This study aimed to assess whether iron replacement versus placebo could improve physical activity in patients with chronic heart failure and iron deficiency. 150 patients for the Iron group and 151 patients to placebo were randomized, physical ability was assessed with the 6 minutes walking test. In the group receiving iron improvement in the 11-meter walk test compared to the placebo group was observed. We also observed an improvement in the quality of life.
Conclusion
Patients with chronic heart failure often have iron deficiency anemia in addition to a reduction in intestinal iron absorption. This work demonstrated an improvement in both the walk test and quality of life with intravenous iron administration.
Piotr Ponikowski
2014-08-31
Original title: Effect of ferric carboxymaltose on functional capacity in patients with heart failure and iron deficiency. CONFIRM-HF.
