Patients eligible for this study suffered from hypertension, had been treated with up to 2 drugs, and presented a daytime ambulatory blood pressure ≥135/85 mmHg and <170/105 mmHg after a 4-week washout period.
The study enrolled 146 patients who were randomized 1:1 to denervation treatment or a sham procedure.
The reduction in daytime ambulatory systolic blood pressure was greater among patients in the denervation arm (-8.5 mmHg) than in the sham arm (-2 mmHg). In consequence, the final adjusted difference was -6.3 mmHg (95% confidence interval: -9.4 to -3.1; p = 0.0001).
Original title: Primary Outcomes of Renal Denervation in the RADIANCE-HTN SOLO Study.
Presenter: Laura Mauri.
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