statins

indicación de tratamiento con estatinas

Anti-Lipid Therapy in PCI Patients: Monotherapy with Statins or Combination?

According to several studies, in patients with high-risk atherosclerotic disease, such as those affected by coronary artery disease, achieving target LDL levels through high-intensity statin therapy has been shown to lead to a significant reduction in long-term cardiovascular events. Therefore, the management of dyslipidemia has become a fundamental pillar of secondary prevention. However, reaching such...

indicación de tratamiento con estatinas

Could Statins Do More than Lower Cholesterol in COVID-19 Patients?

A history of acute myocardial Infarction, cardiac failure or hyperlipidemia has been associated with increased mortality of COVID-19. Observational studies have suggested statins might reduce death risk from COVID-19, in addition to lowering cholesterol.  Statins have anti-inflammatory and antithrombotic effects that could play a role in the course of the infection.  Other studies have arrived...

AHA 2020 | Statins: Confirmed Benefits for the Elderly

Elderly patients (>70) with high cholesterol levels have been systematically excluded from randomized studies on statins, despite their higher risk of cardiovascular events. Presented at AHA 2020 Scientific Sessions and published simultaneously in the Lancet, along comes this primary prevention study including patients between 70 and 100 years of age.  The use of therapies to...

ACC 2020 Virtual | Las estatinas también podrían proteger la cardiotoxicidad de la quimioterapia

Virtual ACC 2020 | Statins Could Also Protect Against Chemotherapy Cardiotoxicity

This retrospective study has shown a reduction in hospitalization for cardiac failure in patients who were already using statins receiving anthracycline and trastuzumab in the context of breast cancer.   The study was to be presented during the ACC 2020 scientific sessions together with the World Congress of Cardiology. However, it had to be called off...

Treat Stroke to Target: terapia agresiva con estatinas post stroke

AHA 2019 | Treat Stroke to Target: Post-Stroke Aggressive Therapy with Statins

Indicating statins to reach more aggressive LDL goals in patients that have suffered transient ischemic attack or ischemic stroke driven by atherosclerosis significantly reduces major cardiovascular events according to this study presented in the AHA 2019 scientific sessions simultaneously published in NEJM. The study was prematurely ended because of lack of funding, but its outcomes...

indicación de tratamiento con estatinas

Statins in Primary Prevention: As Questioned as Aspirin?

This new review, recently published in BMJ, questions the benefit of statins in low-risk primary prevention patients. Authors argue that statins should be more cautiously indicated in primary prevention, considering that their absolute benefit is almost marginal in low-risk patients. Changes in the European guidelines have translated into a wide expansion of patients eligible for...

ACC 2018 | SECURE-PCI: Altas dosis de estatinas previo a la angioplastia podrían ayudar

ACC 2018 | SECURE-PCI: High Dose of Statins pior PCI Could Help

Patients undergoing acute coronary syndrome (ACS) loaded with a high dose of statins prior diagnostic catheterization do not seem to benefit from this strategy. However, when looking at those undergoing PCI alone (excluding all patients who had received surgery or medical treatment), the benefit appears as a reduction of combined major events. The benefit of atorvastatin loading...

STICS: perioperative statins to prevent atrial fibrillation

The aim of this study was to test whether perioperative treatment with rosuvastatin 20 mg could prevent the incidence of postoperative atrial fibrillation and reduce myocardial damage in patients undergoing cardiac surgery. The data showed that rosuvastatin was not effective in preventing the occurrence of atrial fibrillation or reduce myocardial damage measured by troponin.  Barbara...

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