COBRA: culotte technique versus self-expanding dedicated stent to treating bifurcations

This work compared the safety and efficacy of the culotte technique versus the use of self-expanding Biolimus A9 (AXXESS) eluting stent evaluating the healing of the vessel by OCT besides quantitative angiography and clinical events. In one, group (n = 20) bifurcated stent system AXXESS plus everolimus-eluting stents in the main distal branch and side branch and the other group (another 20 patients) the culotte technique plus everolimus eluting stent was used. It ended with kissing balloon using non-compliant balloons in all cases. No significant difference in miointimal coverage of struts evaluated by OCT at 9 months was observed.

In-the culotte group a delay in the miointimal coverage over the proximal segment of the main vessel related to the overlap of the stents was observed. In the AXXESS group, the lumen of proximal main vessel was significantly augmented probably related to the most anatomical sized due to the taper of the self-expanding device. 

Christophe Dubois
2014-05-20

Title: Complex coronary bifurcation lesions – Randomised comparison of a strategy using a dedicated self-expanding biolimus A9-eluting stent versus a culotte strategy using everolimus-eluting stents: primary results of the multicenter COBRA trial

More articles by this author

ORBIT II: atherectomy for heavily calcified lesions

The aim of this study was to evaluate the safety and efficacy of coronary orbital atherectomy system Diamondback to prepare de novo lesions severely...

BABILON: Pharmacological balloon to treat the lateral branch in coronary bifurcations

The paclitaxel-eluting balloon could be an option to minimize the side branch restenosis in coronary bifurcations. In this study, the angiographic and clinical outcomes...

APPOSITION IV: self-expanding DES in acute coronary syndrome

This study was designed to compare the apposition and neointimal coverage of struts by optical coherence tomography (OCT) of the new self-expanding sirolimus  eluting...

MITRAL: First cases of Transcatheter Mitral Valve Implantation (TMVI)

Severe mitral regurgitation is three times more prevalent than aortic stenosis in the elderly population at high risk and poor prognosis if not treated. Fortis...

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Related Articles

SOLACI Sessionsspot_img

Recent Articles

Severe Tricuspid Regurgitation: Surgical vs. Transcatheter Edge-to-Edge Repair

While highly prevalent, tricuspid regurgitation is a notably undertreated valvulopathy. Its progression has been associated with higher mortality and significant disability. According to the...

ACCESS-TAVI: Comparing Post TAVR Vascular Closure Devices

Transcatheter aortic valve replacement (TAVR) is a well-established option to treat elderly patients with severe symptomatic aortic valve stenosis. Technical advances and device development...

Endovascular Treatment of Iliofemoral Disease for the Improvement of Heart Failure with Preserved Ejection Fraction

Peripheral artery disease (PAD) is a significant risk factor in the development of difficult-to-treat conditions, such as heart failure with preserved ejection fraction (HFpEF)....