Pharmacology articles

Saltearse el desayuno y riesgo cardiovascular

Skipping Breakfast and Cardiovascular Risk

Skipping Breakfast and Cardiovascular Risk

Several studies have associated skipping breakfast (having little to no breakfast) with increased cardiometabolic risk factors such as obesity, hypertension, dyslipidemia, diabetes and metabolic syndrome.  This study examined all the available evidence on the association of skipping breakfast and cardiovascular and all-cause mortality. It included 4 studies with close to 200,000 adults (mean age ≥40,

Bebidas azucaradas y con edulcorante asociadas a eventos cardiovasculares y mortalidad

Artificially Sweetened Beverages and Alzheimer Risk

Artificially sweetened beverages (with different kinds of sweeteners) could be responsible for increased cerebrovascular risk and close to a 3-fold increase in dementia risk due to Alzheimer’s disease. Both sweet and artificially sweetened drinks have been associated with cardiometabolic, cerebrovascular and dementia risk. This study prospectively evaluated sweet and sweetened beverage consumption in relation to

Nuevas guías de dislipemia

Egg Consumption and Mortality Due to Cardiovascular Events

According to this study recently published in prestigious journal JAMA, eating too much cholesterol or eggs (which have a high concentration of it in the yolk) is significantly associated with a higher risk of cardiovascular events and all-cause mortality, with a typical dose/effect curve. According to the authors, this information should be considered for an

La complejidad de la angioplastia puede definir el tiempo de doble antiagregación

Ticagrelor Monotherapy One Month After DES Implantation

The GLOBAL LEADERS study includes a pre-specified sub-study, GLASSY, that showed that ticagrelor monotherapy after one month of dual antiplatelet therapy is non-inferior (but not superior) to conventional treatment in terms of ischemic events. As regards safety, ticagrelor monotherapy did not decrease major bleeding compared with conventional therapy. The GLOBAL LEADERS randomized 15,991 patients who required

Bebidas azucaradas y con edulcorante asociadas a eventos cardiovasculares y mortalidad

Sugar-Sweetened Beverages and Artificially Sweetened Beverages Associated with Cardiovascular Events and Mortality

While the consumption of carbonated soft drinks has decreased in most Western countries over the last 20 years, these are still the main source of simple sugars in our diet. The World Health Organization recommends 25-50 g of simple sugars per day, a dose covered with a single can of a carbonated soft drink. For other associations,

Pretratamiento con estatinas para prevenir eventos peri angioplastia carotidea

Secondary Prevention: A Responsibility We Should Not Delegate

After coronary angioplasty, the use of drugs whose efficacy for the reduction of major events has been proven declines over time, which is associated with worse patient prognosis. Sometimes, without meaning to, we convey to patients the idea that, once the stent has been implanted, the artery is “cured” or that the only potential future

anticoagulated patients that receive angioplasty

Benefit of Anticoagulation in the Elderly with Atrial Fibrillation

Guidelines recommend oral anticoagulation for all ≥ 75-year-old patients with atrial fibrillation. However, there is little evidence as to its net clinical benefit in the elderly population. This study looked at the life net clinical benefit in atrial fibrillation patients over 75 years of age treated with warfarin or apixaban vs. no treatment. Researchers observed

Resultados a 5 años del cierre de orejuela

Net Benefit of Left Atrial Appendage Closure vs. Anticoagulation in Atrial Fibrillation

This analysis shows that the long-term clinical benefit of left atrial appendage closure with Watchman is superior to warfarin in patients with atrial fibrillation (AF). The initial peri-procedural risks of device implantation are counterbalanced over time, with reduced risk of bleeding and death.  The PROTECT-AF (Watchman Left Atrial Appendage Closure Technology for Embolic Protection in

Treat Stroke to Target: terapia agresiva con estatinas post stroke

AHA 2019 | Treat Stroke to Target: Post-Stroke Aggressive Therapy with Statins

Indicating statins to reach more aggressive LDL goals in patients that have suffered transient ischemic attack or ischemic stroke driven by atherosclerosis significantly reduces major cardiovascular events according to this study presented in the AHA 2019 scientific sessions simultaneously published in NEJM. The study was prematurely ended because of lack of funding, but its outcomes

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