DISCOVER FLOW: Correlation of conventional FFR vs non invasive FFR obtained with MSCT for successful stenting.

The DISCOVER FLOW trial has recently showed an excellent correlation between fractional flow reserve values (FFR) traditionally obtained with coronary CT angiography (CCTA) and the ones obtained with a non invasive technology derived from multi slice computerized tomography (MSCT). Researchers used a novel technology that allows deriving non invasive FFR from MSCT data. Dr. Bon-Kwon Koo (Seoul National University, Korea) won 2011 Innovation Award at the EuroPCR for this breakthrough technology. In this opportunity, Dr. Koo compared post-stenting FFR in 43 patients (48 lesions), measured during procedure, to the pre-procedure simulation with MSCT. In addition to basal non invasive evaluation of FFR, this novel technology enables FFR estimation after virtual stenting of each of the observed lesions. When compared to invasive after stenting FFR measured during procedure, an acceptable correlation was observed (r=0,55, p<0,01) with an absolute difference of only 0.02±0.05. Compared to the invasive evaluation, FFR-MSCT presented a 100% sensitivity, 96% specificity, with a predictive negative power of 100% to detect unsatisfactory results (FFR≤0,08). These results suggest this fascinating imaging technology not only enables stenting success prediction, but also treatment planning and stent length and site selection to obtain FFR >0,8 values.

bon-kwon-koo
Bon-Kwon Koo
2012-05-16

More articles by this author

CLI-OPCI: Optical coherence tomography (OCT)-guided stent implantation vs. conventional angiography guided angioplasty.

CLI-randomized study CLI-OPCI (n = 670, 1:1) evaluated the impact of stent implantation guided by angiography and optical coherence tomography (OCT), versus angioplasty guided...

TROFI: Minimal intra-stent flow area in STEMI patients post primary PCI with or without manual thrombus aspiration.

Professor Serruys presented the results of the TROFI trial that compares the minimal intra-stent flow area in STEMI patients post primary PCI with or...

DESolve I FIM: Evaluation of a FIM trial results of a bioabsorbable stent (15 patients).

 This trial is a prospective evaluation of DESolveTM bioabsorbable coronary stent implantation in a 15 patient cohort enrolled in New Zealand and Belgium. At...

SMART: Manual Thrombectomy vs. Rheolytic Aspiration in ST-segment Elevation Acute Myocardial Infarction.

Dr. David Antoniucci presented the immediate results of randomized trial SMART SMART (n=80, 1:1) comparing manual thrombectomy (MAT) vs. rheolytic aspiration (RT) in the...

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Related Articles

SOLACI Sessionsspot_img

Recent Articles

Percutaneous Tricuspid Valve Replacement with Lux-Valve

Tricuspid regurgitation (TR) is a condition associated with poor quality of life, frequent hospitalizations due to heart failure, and increased mortality, even under optimal...

Transcatheter Pulmonary Valve Implantation with a Self-Expanding Valve: Outcomes at 3 Years

Pulmonary regurgitation (PR) is a common condition in patients who have undergone surgical repair of Tetralogy of Fallot or other pathologies involving the right...

Radial Patency in Coronary Procedures: Is Heparin Enough or Should We Aim for Distal Transradial Access?

Transradial access is the preferred route in most coronary procedures due to its proven reduction in mortality compared to transfemoral access. However, one of...