The goal of this study was to assess the efficacy of low doses of aspirin (AAS) for primary prevention of cardiovascular events in Japanese elderly patients with multiple risk factors for arteriosclerosis but with no history of heart disease.
This open study included patients between 60 and 85 with risk factors such as high blood pressure, dyslipidaemia or diabetes, between 2005 and 2007 and randomized them to enteric coated aspirin 100 mg once daily or placebo. 80.4% of patients had more than 3 of the listed risk factors.
Over a 5 year follow up no significant differences were observe between the groups. (p=0.54).
Conclusion
Aspirin was not associated with a significant reduction of cardiovascular events rate in elderly patients with multiple cardiovascular risk factors.
1_kazuyuki_shimada_presentacion
Kazuyuki Shimada
2014-11-18
Original title: Low-Dose Aspirin for Primary Prevention of Cardiovascular Events in Elderly Patients With Multiple Atherosclerotic Risk Factors: A Randomized Controlled Trial.