PARTNER II: Less oversizing to reduce paravalvular failure with the new generation of SAPIEN 3

The new generation SAPIEN 3 valve was designed to reduce paravalvular aortic regurgitation. The objective of this work was to evaluate the influence of “oversizing” for SAPIEN 3 valve both in relation to the area and the perimeter and determine if calcium ring influences the degree of failure.

A lesser degree of oversizing need it to prevent moderate to severe aortic failure was observed. Being the ideal valve size 0 to 5% more than the size of the ring. The higher the valvular calcification degree index, higher the degree of aortic failure post procedure.

Conclusion

The study showed SAPIEN 3valve has low rate of moderate to severe aortic regurgitation in a low oversizing scenario.

Philipe Blanke
2015-05-20

Original title: Influence of computed tomography-based over-sizing on the incidence of paravalvular regurgitation of a new-generation transcatheter valve: early results of the intermediate-risk S3 cohort PARTNER II trial.

More articles by this author

NONSTEMI: Superiority of early angioplasty in non-ST elevation myocardial infarction

The European guidelines recommend revascularization within 24 hours in high-risk patients with No ST segment elevation myocardial infarction. It is unclear whether these patients...

TOTAL stroke: increased risk of stroke with thromboaspiration

There are many doubts about the benefit of manual thromboaspiration, not only in terms of improvement of the clinical end point but also the...

IN.PACT Global Study: Pharmacological balloon in long lesions of the Superficial Femoral Artery (SFA)

Long lesions (≥ 15 cm), total occlusions, and in-stent restenosis represent a unique treatment challenge in peripheral vascular disease. IN.PACT Global study is a...

Angiographic TOTAL: Sub angiography studio of TOTAL

Myocardial blush is a predictor of mortality after primary angioplasty. Small studies showed a degree of improvement blush with manual thromboaspiration. The present work...

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Related Articles

SOLACI Sessionsspot_img

Recent Articles

Long-Term Predictors of Valve Deterioration After TAVI

Transcatheter aortic valve implantation (TAVI) has become an innovative technology for the treatment of patients with severe aortic valve stenosis. Initially implemented in elderly...

Coronary access after TAVI with fourth- and fifth-generation Evolut valves: the EPROMPT-CA study

The expansion of transcatheter aortic valve implantation (TAVI) toward younger and lower-risk patients has increased the relevance of post-procedural coronary access. In this context,...

Morpheus Global Registry: Safety and efficacy of the long tapered BioMime™ Morph stent in complex coronary lesions

Percutaneous coronary intervention in long coronary lesions continues to represent a technical and clinical challenge, in which the use of conventional cylindrical stents may...