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DAPT TRIAL: double antiaggregation remains controversial

Article This multicenter randomized control study with placebo was designed to determine the risks and benefits of double...

ISAR-SAFE: 6 vs. 12 month clopidogrel administration after DES implantation

The aim of this randomized double blind control trial was to validate the safety and efficacy of...

Reduction of ischemic events after 30 months of prasugrel following TAXUS stent implantation

Article The TAXUS Liberté Post Approval study included patients treated with TAXUS paclitaxel DES receiving prasugrel for 12...

IMPROVE-IT Trial: Finally the association of ezetimibe and simvastatin reduces events vs. simvastatin monotherapy

This is a multicenter, randomized, double blind study designed to test the hypothesis that the combination of...

FACTOR 64: Routine coronary CT angiography in patients at high risk for heart disease.

Article 900 patients with asymptomatic diabetes mellitus were randomized to CT angiography vs. Standard management. Primary end point...

ODYSSEY ALTERNATIVE: Monoclonal antibody alirocumab vs. ezetimibe in patients with statin intolerance

Statin intolerance limits patients’ capacity to reach their LDL goals. This study compared the new drug alirocumab...

Low doses of aspirin for primary prevention in elderly patients with multiple risk factors.

Article The goal of this study was to assess the efficacy of low doses of aspirin (AAS) for...

NONI: Inhaled nitric oxide to reduce reperfusion injury in myocardial infarction

Infarct size is an independent predictor of survival and ventricular function. Several alternatives have been tried to...