Diabetes mellitus patients generally present more diffuse coronary disease, faster lesion progression and higher risk of restenosis after PCI. The way these anatomical differences translate into in a different clinical practice, compared to non-diabetic patients, remains unclear. Prior studies comparing the frequency of angina symptoms in diabetic vs. non-diabetic patients have arrived to contradicting outcomes,…
Severity of Lesions Assessed by FFR in Coronary Disease: Is It Associated with Major Events?
In patients with coronary disease, the prognosis depends on the extent and reversibility of myocardial ischemia. Whether the outcome also depends on the severity of stenosis as determined by fractional flow reserve (FFR) has not been studied yet. This study investigates the relationship between fractional flow reserve values and vessel-related events. Major adverse cardiovascular…
Beta-Blockers for Revascularized Patients: To Prescribe or Not?
This study examines predictors and outcomes associated with the prescription of beta-blockers at discharge after a successful coronary angioplasty in patients with stable chronic angina WITHOUT prior history of acute myocardial infarction or heart failure. The benefit of beta-blockers in patients with acute myocardial infarction or systolic heart failure is well documented. However, their…
Stem Cells: A New Alternative for Refractory Angina?
Courtesy of Dr. Agustín Vecchia. Recent investigations and certain randomized trials suggest that the administration of CD34+ stem cells to patients with refractory angina improves exercise tolerance and decreases angina frequency. The following is a phase 3, randomized, double-blind multicenter trial comparing three groups of patients: active treatment through intramyocardial administration of CD34+ stem cells (autologous, purified), standard of care…
FFRangio: New Software Derives FFR Value from Angiography
Original Title: Image-based FFR during coronary catheterization. Presenter: Mariano Pellicano. Fractional flow reserve (FFR) is considered the gold standard to detect myocardial ischemia; however, due to its elevated cost, increased procedural time and potential complications associated to the guiding catheter, it is still underused. The FFRangio is a new technology based of angiographic images…
Heart Disease with Typical Symptoms and Negative Stress Test
Original Title: Effect of the presence and type of angina on cardiovascular events in patients without known coronary artery disease referred for elective coronary angiography. Reference: Vavalle JP et al. JAMA Cardiology 2016; Epub ahead of print. Patients presenting typical angina with a negative stress test result prior catheterization have a high rate of heart…
- 1
- 2