Fenestrated prosthetics versus surgery for aneurysms of the abdominal aorta with hostile neck

Original title: Comparison of fenestrated endovascular and open repair of abdominal aortic aneurysms not suitable for standard endovascular repair. Reference: Rana Canavati et al. J Vasc Surg 2013;57:362-7.

Studies in patients with infrarenal abdominal aortic aneurysm that could receive a standard stent versus conventional surgery, showed reduced perioperative mortality with endovascular treatment

However, these same results in patients with unsuitable necks for standard treatment (pararenal aneurysms or juxtarenal) requiring a fenestrated stent, are unclear. All 107 patients with abdominal aortic aneurysm and unsuitable neck for standard therapy, were eligible for the study, of whom 54 received surgery and 53 patients, fenestrated endograft (Zenith fenestrated stentgraft Cook UK Ltd, Hitchin, UK).

In the postoperative 30 patients, (56%) in the surgical group and 18 patients (34%) in the endovascular group, presented complications. This difference in favor of endovascular treatment was significant (p = 0.045) as well as the total number of early reoperation (p = 0.04) and hospital stay (mean 12 days for surgery versus 7 days for endovascular, P = 0.0001). At 30-days, mortality was 9.2% (5 patients) for the surgical group and 3.7% (2 patients) for the endovascular group.

Conclusion: 

This single-center analysis showed that fenestrated endovascular stenting treatment, is associated with a reduction in mortality, morbidity and hospital stay, compared with surgery in patients with abdominal aortic aneurysm with unsuitable neck.

Commentary:

With several methodological limitations, this study is hypothesis-generating to perform prospective and randomized jobs. An example of this, is that in almost half of patients in the surgical group, it was not technically possible the fenestrated prosthesis implantation, these patients were operated because it was their only option. Similarly in the endovascular group, many surgical patients were discarded by severe multiple comorbidities. The cohorts were different in many ways, so the results should be interpreted in this context.

SOLACI.ORG

More articles by this author

Impact of Baseline Systolic Blood Pressure on Blood Pressure Changes Following Renal Denervation

Renal denervation (RDN) is a guideline-recommended therapy to reduce blood pressure in patients with uncontrolled hypertension, although uncertainties remain regarding which factors best predict...

Hypertriglyceridemia as Key Factor to Abdominal Aortic Aneurysm Development and Rupture: Genetic and Experimental Evidence

Abdominal aortic aneurysm (AAA) is a deadly vascular disease with no effective drug treatment, and risk of rupture reaching up to 80%. Even though...

Atrial Fibrillation and Chronic Kidney Disease: Outcomes of Different Stroke Prevention Strategies

Atrial fibrillation (AF) affects approximately 1 in every 4 patients with end-stage renal disease (ESRD). This population carries a high burden of comorbidities and...

Safety of Prophylactic Spinal Fluid Drainage in Open and Endovascular Repair of Thoracic and Thoracoabdominal Aortic Aneurysms

Spinal cord injury remains one of the most devastating complications of thoracic and thoracoabdominal aneurysm repair, mainly associated to a compromised the Adamkiewicz artery...

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Related Articles

SOLACI Sessionsspot_img

Recent Articles

Coronary Perforations and Use of Covered Stents: Safe and Effective Long-Term Strategy?

Coronary perforations remain one of the most serious complications of percutaneous coronary intervention (PCI), especially in cases of Ellis ruptures type III. In these...

Is it really necessary to monitor all patients after TAVR?

Conduction disorders (CD) after transcatheter aortic valve replacement (TAVR) are a frequent complication and may lead to the need for permanent pacemaker implantation (PPI)....

Is it really necessary to monitor all patients after TAVR?

Conduction disorders (CD) after transcatheter aortic valve replacement (TAVR) are a frequent complication and may lead to the need for permanent pacemaker implantation (PPI)....