Fenestrated prosthetics versus surgery for aneurysms of the abdominal aorta with hostile neck

Original title: Comparison of fenestrated endovascular and open repair of abdominal aortic aneurysms not suitable for standard endovascular repair. Reference: Rana Canavati et al. J Vasc Surg 2013;57:362-7.

Studies in patients with infrarenal abdominal aortic aneurysm that could receive a standard stent versus conventional surgery, showed reduced perioperative mortality with endovascular treatment

However, these same results in patients with unsuitable necks for standard treatment (pararenal aneurysms or juxtarenal) requiring a fenestrated stent, are unclear. All 107 patients with abdominal aortic aneurysm and unsuitable neck for standard therapy, were eligible for the study, of whom 54 received surgery and 53 patients, fenestrated endograft (Zenith fenestrated stentgraft Cook UK Ltd, Hitchin, UK).

In the postoperative 30 patients, (56%) in the surgical group and 18 patients (34%) in the endovascular group, presented complications. This difference in favor of endovascular treatment was significant (p = 0.045) as well as the total number of early reoperation (p = 0.04) and hospital stay (mean 12 days for surgery versus 7 days for endovascular, P = 0.0001). At 30-days, mortality was 9.2% (5 patients) for the surgical group and 3.7% (2 patients) for the endovascular group.

Conclusion: 

This single-center analysis showed that fenestrated endovascular stenting treatment, is associated with a reduction in mortality, morbidity and hospital stay, compared with surgery in patients with abdominal aortic aneurysm with unsuitable neck.

Commentary:

With several methodological limitations, this study is hypothesis-generating to perform prospective and randomized jobs. An example of this, is that in almost half of patients in the surgical group, it was not technically possible the fenestrated prosthesis implantation, these patients were operated because it was their only option. Similarly in the endovascular group, many surgical patients were discarded by severe multiple comorbidities. The cohorts were different in many ways, so the results should be interpreted in this context.

SOLACI.ORG

More articles by this author

Transcatheter Pulmonary Valve Implantation with a Self-Expanding Valve: Outcomes at 3 Years

Pulmonary regurgitation (PR) is a common condition in patients who have undergone surgical repair of Tetralogy of Fallot or other pathologies involving the right...

RACE Trial: Effect of Balloon Pulmonary Angioplasty and Riociguat on Right Ventricular Afterload and Function in Chronic Thromboembolic Pulmonary Hypertension

Even though pulmonary endarterectomy is the treatment of choice for chronic thromboembolic pulmonary hypertension (CTEPH), up to 40% of patients are not candidates because...

ACC-2025 Congress Second Day Key Studies

BHF PROTECT-TAVI (Kharbanda RK, Kennedy J, Dodd M, et al.)The largest randomized  trial carried out across 33 UK centers between 2020 and 2024, assessing...

ACC 2025 | API-CAT: Reduced vs. Full Dose Extended Anticoagulation in Patients with Cancer Related VTE

The risk of cancer related recurrent venous thromboembolism (VTE) will drop over time, while bleeding risk will persist. At present, it is recommended we...

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Related Articles

SOLACI Sessionsspot_img

Recent Articles

Pretreatment with DAPT in Acute Coronary Syndrome: An Ongoing Debate?

In acute coronary syndrome (ACS) dual antiplatelet therapy (DAPT) has become a fundamental pillar after percutaneous coronary intervention (PCI), preventing stent thrombosis and acute...

Measuring Post-TAVI Gradients and Their Implications: Are Invasive and Echocardiographic Assessments Comparable?

Transcatheter aortic valve implantation (TAVI) is considered the treatment of choice for a significant proportion of patients with symptomatic aortic stenosis. Outcomes have improved...

Another Blow for Intra-Aortic Balloon Pumo Counterpulsation? Randomized Study on Its Use in Chronic Heart Failure Progressing to Cardiogenic Shock

Cardiogenic shock (CS) remains a condition with extremely high mortality (around 50%). While most therapies for this pathology have been studied in CS secondary...