Current guidelines suggest treating only the culprit artery of myocardial infarction with ST-segment elevation. This prospective and randomized work included 296 patients in 7 centers suffering ST-segment elevation acute myocardial infarction referred for primary angioplasty randomized to treat only the culprit artery (n = 146) versus complete revascularization (n = 150).
In the culprit artery group, 90% of drug-eluting stents were used and in the complete revascularization group 95%. One year follow-up, the primary end point was a composite of death, myocardial infarction, heart failure and the need to repeat revascularization was significantly lower in the complete revascularization group (10% versus 21.1%, P = 0.009). The procedure time and contrast volume were obviously higher in the complete revascularization group. No differences in major bleeding, stroke or contrast nephropathy were observed.
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Anthony H Gershlick
2014-09-01
Original title: Complete versus lesion only primary -PCI Trial (CvLPRIT): Treat the infarct related artery only or all lesions.