ILUMIEN II: OCT guided stenting versus IVUS

The main predictor of adverse outcomes (thrombosis and restenosis) after implantation of a stent is the degree of expansion according to published studies using coronary intravascular ultrasound (IVUS). It is unknown whether optical coherence tomography (OCT), in this sense, provides similar information as the IVUS. The aim of this study was to compare the degree of expansion of the stent after angioplasty guided by IVUS or OCT. We included patients from ILUMIEN 1 study (n = 354) and the ADAPT-DES study (n = 586) and compared using propensity score which left 286 patients in each arm for the final analysis. The primary end point of the study was the percentage of stent expansion post angioplasty defined as the minimum lumen area divided by the average reference area. The degree of expansion of the stent was not significantly different between groups, as malapposed rate, residual protrusion, and edge dissection.

Conclusion

Both IVUS and OCT were associated with a similar rate of expansion, malapposed, residual protrusion, and edge dissection after stent angioplasty.

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G.W. Stone
2015-05-20

Original title: A Retrospective Evaluation of Stent Expansion with OCT Guidance vs. IVUS Guidance. ILUMIEN II trial.

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