SCOT-HEART: Coronary angiography by tomography in patients with suspected coronary artery disease

The aim of this study was to evaluate Coronary angiography by multislice CT compared with standard therapy in patients at low or moderate risk with suggestive symptoms of coronary artery disease. 2073 patients were included in each branch with a mean follow up of 1.7 years. CT significantly increased the certainty of the diagnosis of angina due to obstructive coronary disease compared with standard management (RR = 1.79, CI 95% 1.62 to 1.96, p <0.001).

The revascularization rate was not statistically significant but showed a tendency to be more frequent in the CT branch (11.2% versus 9.7%; p = 0.061). The clinical end point of death and infarction was similar between the two branches (1.3% versus 2.0%; p = 0.053).

Conclusion

In symptomatic patients by angina and with low or moderate risk the Coronary angiography by multislice CT increases the certainty of the diagnosis of coronary disease.

David E. Newby
2015-03-17

Original title: CT coronary angiography in patients with suspected angina due to coronary heart disease. An open-label, parallel-group, multicentre trial.

More articles by this author

OSLER: Evolocumab reduces cardiovascular events compared with standard statin therapy

The aim of this study was to evaluate the safety and efficacy of long-term Evolocumab, an inhibitor of PCSK9 added to standard therapy versus...

ODYSSEY LONG TERM: alirocumab reduces LDL in patients with maximum tolerated doses of statins

The aim of this study was to evaluate treatment with alirocumab a monoclonal antibody against PCSK9 receptor, compared with placebo in patients with heterozygous...

NOTION: TAVR in low-risk patients

The aim of this study was to compare the results of transcatheter aortic valve replacement (TAVR) versus surgery in unselected patients with severe degenerative...

EMBRACE STEMI: Bendavia a new drug to prevent mitochondrial dysfunction in AMI.

The purpose of this phase 2 study was to test the safety and efficacy of new drug bendavia to prevent mitochondrial dysfunction. It was...

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Related Articles

SOLACI Sessionsspot_img

Recent Articles

CRT 2026 | TAVI-CLOSE Trial: Dual Suture vs Suture + Plug for Vascular Closure After Transfemoral TAVI

The transfemoral approach is the predominant strategy for transcatheter aortic valve implantation (TAVI). Although vascular complications are currently less frequent, they remain relevant determinants...

CRT 2026 | NAVITOR IDE: Hemodynamic Outcomes and 5-Year Durability of an Intra-Annular Self-Expanding Transcatheter Aortic Valve

As TAVI expands into younger populations and patients with lower surgical risk, prosthesis durability has become a key aspect of long-term management. The NAVITOR...

CRT 2026 | CUT-DRESS Trial: Lesion Preparation with Cutting Balloon

In-stent restenosis (ISR) continues to represent a relevant clinical challenge in contemporary coronary angioplasty practice. Despite advances in drug-eluting stents, neointimal hyperplasia and suboptimal...