STAMPEDE Trial: Bariatric surgery was superior to optimal medical therapy to glycemic control in obese type 2diabetics

In the short term, bariatric surgery showed improvement in glycemic control of obese type 2 diabetics.This study evaluated the course at 3 years of 150 obese type 2 diabetic patients randomized to intensive medical therapy or intensive clinical treatment plus bariatric surgery. The primary endpoint was a glycosylated hemoglobin of 6% or less.The mean age of patients was 48 ± 8 with 68% of women; glycosylated hemoglobin at baselinewas at 9.3 ± 1.5 % and body mass index 36.0 ± 3.5.At 3 years follow-up, the primary end point was reached for about 5% of patients in the medical treatment group and 38% of patients in the medical treatment group plus bariatric surgery (p < 0.001).The use of hypoglycemic medication including insulin was lower in the surgical group.

Conclusion

Among obese patients with uncontrolled type 2 diabetes, bariatric surgery with medical treatment to 3 years resulted in better glycemic control than medical treatment alone.

Article

5_sangeeta_kashyap_slides
Sangeeta R Kashyap
2014-03-31

Original title: Effect of Bariatric Surgery vs. Intensive Medical Therapy on Long-term Glycemic Control and Complications of Diabetes: 3-Year STAMPEDE Trial Results.

More articles by this author

MSC -HF Trial: Auto mesenchymal cell transplantation may improve ventricular function in patients with heart failure of ischemic cause

This study is a phase 2, randomized 2:1, double blind, and placebo-controlled included 59 patients with advanced heart failure of ischemic etiology undergoing autologous...

ZEUS Trial: Patients with increased risk of bleeding may benefit from eluting stents Zotarolimus

The use of drug-eluting stents versus bare metal stents is controversial in some clinical situations in patients at high risk of bleeding.This study randomized...

NEXT Trial: Biodegradable polymer stent (Nobori) was similar to the permanent polymer stents (Xience / Promus) at 2 years.

This multicenter work from Japanrandomized 3200 patients to receive biodegradable polymer biolimus eluting stent(Nobori) or everolimus-eluting stent with permanent polymer (Xience / Promus). The...

SIRS Trial: Methylprednisolone does not decrease mortality and increase the risk of stroke in patients undergoing cardiac surgery

Cardiac surgery with cardiopulmonary bypass results in an inflammatory response of the body that is usually associated with adverse outcome. The preventive use of...

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Related Articles

SOLACI Sessionsspot_img

Recent Articles

Severe Tricuspid Regurgitation: Surgical vs. Transcatheter Edge-to-Edge Repair

While highly prevalent, tricuspid regurgitation is a notably undertreated valvulopathy. Its progression has been associated with higher mortality and significant disability. According to the...

ACCESS-TAVI: Comparing Post TAVR Vascular Closure Devices

Transcatheter aortic valve replacement (TAVR) is a well-established option to treat elderly patients with severe symptomatic aortic valve stenosis. Technical advances and device development...

Endovascular Treatment of Iliofemoral Disease for the Improvement of Heart Failure with Preserved Ejection Fraction

Peripheral artery disease (PAD) is a significant risk factor in the development of difficult-to-treat conditions, such as heart failure with preserved ejection fraction (HFpEF)....