STAMPEDE Trial: Bariatric surgery was superior to optimal medical therapy to glycemic control in obese type 2diabetics

In the short term, bariatric surgery showed improvement in glycemic control of obese type 2 diabetics.This study evaluated the course at 3 years of 150 obese type 2 diabetic patients randomized to intensive medical therapy or intensive clinical treatment plus bariatric surgery. The primary endpoint was a glycosylated hemoglobin of 6% or less.The mean age of patients was 48 ± 8 with 68% of women; glycosylated hemoglobin at baselinewas at 9.3 ± 1.5 % and body mass index 36.0 ± 3.5.At 3 years follow-up, the primary end point was reached for about 5% of patients in the medical treatment group and 38% of patients in the medical treatment group plus bariatric surgery (p < 0.001).The use of hypoglycemic medication including insulin was lower in the surgical group.

Conclusion

Among obese patients with uncontrolled type 2 diabetes, bariatric surgery with medical treatment to 3 years resulted in better glycemic control than medical treatment alone.

Article

Original title: Effect of Bariatric Surgery vs. Intensive Medical Therapy on Long-term Glycemic Control and Complications of Diabetes: 3-Year STAMPEDE Trial Results.