OPINON: OCT vs. IVUS Guided PCI

Original Title: Optical frequency domain imaging vs. IVUS in PCI: the OPINION trial – one-year primary endpoint results.
Presenter: T. Kubo.

 

Optical coherence tomography (OCT) is increasingly being used in the daily practice given its greater capacity to define anatomical structures vs. intravascular ultrasound (IVUS). The clinical impact of this decision remains unclear.

 
This study was designed as non-inferiority; 800 patients were randomized 1:1 to OCT guided PCI vs. IVUS guided PCI, and they all received the Nobori DES.

 
Angiographic follow up was at 8 and 12 months. Primary end point was target vessel failure (combination of cardiovascular death, target vessel infarction and clinically justified target vessel revascularization).

 
There were no differences between the groups in procedural success rate, stent diameter or total number of stents. Primary end point incidence was 5.2% for the OCT group and 4.9% for the IVUS group (p<0.05 for non-inferiority). As regards primary end point component rates, separately, no differences were found.

 

Conclusion
OCT guided PCI vs. IVUS guided PCI showed similar clinical and angiographic events at 12 months. In both groups, death and target vessel infarction incidence were extremely low.

opinion

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