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euroPCR 2014.

The most relevant articles and presentations, daily report from the euroPCR 2014 - May, 20 to 23.

Ernesto Torresani, Ricardo Lluberas, Oscar Mendiz, Jorge Belardi,  José Luis Leiva Pons and Fernando Pineda at the SOLACI@euroPCR Session "Appraisal of new technologies in interventional medicine" held  on Tuesday 20th, in Theatre Havane, under the euroPCR Congress 2014

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ORBIT II: atherectomy for heavily calcified lesions
The aim of this study was to evaluate the safety and efficacy of coronary orbital atherectomy system Diamondback to prepare de novo lesions severely calcified to stent implantation. This orbital ...

TRYTON: dedicated stent for bifurcations not inferior than the provisional technic
This study compared the clinical and angiographic results of the use of the provisional stent technique versus the 2 stents technique (TRYTON device at the side branch) in true bifurcations.  ...

COBRA: culotte technique versus self-expanding dedicated stent to treating bifurcations
This work compared the safety and efficacy of the culotte technique versus the use of self-expanding Biolimus A9 (AXXESS) eluting stent evaluating the healing of the vessel by OCT besides ...

MITRAL: First cases of Transcatheter Mitral Valve Implantation (TMVI)
Severe mitral regurgitation is three times more prevalent than aortic stenosis in the elderly population at high risk and poor prognosis if not treated. Fortis mitral valve was designed using ...

BABILON: Pharmacological balloon to treat the lateral branch in coronary bifurcations
The paclitaxel-eluting balloon could be an option to minimize the side branch restenosis in coronary bifurcations. In this study, the angiographic and clinical outcomes of paclitaxel-eluting balloon ...

APPOSITION IV: self-expanding DES in acute coronary syndrome
This study was designed to compare the apposition and neointimal coverage of struts by optical coherence tomography (OCT) of the new self-expanding sirolimus  eluting stent (STENTYS SES) at 4 ...

ROBUST: Routinely use of OCT in primary angioplasty with DES showed no benefit
This work aimed to evaluate the use of optical coherence tomography (OCT) to guide the drug-eluting stent implantation during primary angioplasty. 201 patients experiencing STEMI to use or not OCT ...

IBERIAN: appendage occlusion registry
The aim of this study was to observe the rate of thromboembolic and hemorrhagic events in a period of 2 years in 167 patients undergoing appendage occlusion with Amplatzer device.  Appendage ...

TRIPLETE RESET trial: comparison of platelet reactivity with clopidogrel, prasugrel or ticagrelor.
The individual variability to platelet response of clopidogrel is related to several mechanisms with high intrinsic platelet reactivity, variability in drug metabolism, drug interactions, etc. The ...

COMPARE II: biolimus eluting stent with biodegradable polymer versus everolimus at 3 years.
This study randomized 2:1 - 2707 patients to biolimus eluting stent with biodegradable polymer versus everolimus eluting stent with permanent polymer. At one year, the results were similar ...

PARIS register: Non-adherence impact to antiplatelet therapy among men and women
The PARIS registry was a prospective observational study in 5018 patients undergoing coronary angioplasty with stent implantation in 15 centers. Three categories were prespecified in the ...

Meta-analysis confirms the reduction in ischemic events with 2nd generation DES versus BMS
This paper included 5 studies that randomized patients to conventional stent versus chromium cobalt everolimus eluting stent; at 2 years, a significantly lower risk of cardiac death (2.7% for the ...

Bivalirudin superior than heparin beyond the use or not of Glycoprotein inhibitors
Bivalirudin benefits in bleeding events versus heparin plus glycoprotein IIbIIIa inhibitors is clear even though  this benefit has not been fully studied at the point whether persists when ...

DESSOLVE II: 2-year results show the superiority of the sirolimus eluting stent with fast bio -absorbable polymer.
The aim of this study was to evaluate the performance of the sirolimus eluting stent with bio -absorbable polymer (MiStent SES) compared with zotarolimus eluting stent with permanent polymer ...

ACCOAST: pretreatment with prasugrel in non-ST elevation acute coronary syndrome (NSTE-ACS) offers no benefit and increased bleeding
P2Y12 receptor inhibitors are effective in patients experiencing NSTE-ACS, however, the administration timing is not clear. This study evaluated the administration of prasugrel at the time of ...

SORT-OUT V: Similar results of biolimus eluting stent with biodegradable polymer versus sirolimus eluting stent with permanent polymer.
The last results of the SORT OUT V submitted in PCR 2012 showed that biolimus eluting stent with  biodegradable polymer was not able to reach the non-inferiority versus sirolimus eluting stent ...

BLESS: assessment of platelet reactivity in patients undergoing angioplasty receiving prasugrel.
The aim of this study was to evaluate the modification in residual platelet reactivity by adjusting the prasugrel dose from 10 mg to 5 mg after the acute phase (1 month) of ACS. 450 patients were ...

Safety and efficacy of Cardiobrand device for percutaneous mitral annuloplasty
The Cadiobrand device is implanted through a transseptal approach and makes a reduction in the mitral annulus area. The study included 24 patients with moderate mitral regurgitation (functional ...

SALUS: New percutaneous valve with promising results regarding aortic regurgitation post implant.
Aortic regurgitation after valve implantation has been shown to be a long -term mortality predictor. The aim of this study was to test the new Direct Flow Medical system, which is more flexible ...

SOURCE XT: Results at 2 years of SAPIEN XT valve
Multicenter prospective study included 2688 patients with a mean age of 81.4 years and 20.5 EuroScore. The all-cause mortality at 2 years was 27.7% (31.5% SOURCE study). The incidence of stroke at 2 ...

NOBORI II: Final 5-year results of drug-eluting stent with bio-absorbable polymer
This study evaluated the performance of Nobori biolimus bio-absorbable polymer stent in real-world patients. A total of 3067 consecutive patients followed up to 5 years were included. The rate of ...

TRYTON dedicated bifurcation stent in left main coronary artery
TRYTON is a cobalt chromium device specifically dedicated for bifurcation lesions to be implanted in the side branch. Circumflex artery is the major lateral branch fund the coronary tree. Between ...

POST -IT: The FFR modifies strategy in almost half of patients
The use of FFR to guide treatment showed improved outcomes in previous studies. However, there are few data on the routine use of the method and its impact on modifying therapeutic decisions for ...

DISCOVER Trial: Results at one year of the new nonmetallic percutaneous aortic valve
Direct Flow Medical prosthesis is a nonmetallic, repositionable, recaptured valve (even after posts dilate), that does not require a pacemakers use during both implantation and ...

UK TAVI Registry: Long-term results of TAVI in the UK
This record has been created in order to evaluate the results of percutaneous aortic valve replacement in the UK and currently includes more than 4500 patients with 100% follow-up for mortality. The ...

REDUCE-HTN: safety and efficacy of new bipolar device for renal denervation
This study included 146 patients with resistant hypertension who were medicated with an average of 5.4 drugs. Preliminary 18-month data showed a significant reduction of blood pressure values ...

ADVANCE II: Low incidence of permanent pacemaker for self -expandable valve
The incidence of permanent pacemaker implantation (PPM) is variable between the different series within 30 days of the aortic valve implantation with the CoreValve prosthesis. The aim of this study ...

TITAN-AMI: Final results of bio-active coated stent
Previous studies suggest the excellent performance of the bioactive coated stent TITAN 2 compared with drug-eluting stents (DES). The aim of the study was to evaluate the results of this device in ...

SIMPLICITY HTN -3: subgroup analysis identifies potential confounders
Initial studies showed a blood pressure significant reduction to 3 years in patients with resistant hypertension, while the SIMPLICITY HTN -3 with a larger number of patients compared to a group ...

Safety and efficacy of a new multi-electrode device for simultaneous renal ablation
This study aimed to establish the safety and effectiveness of renal denervation using the new multielectrode device (EnligHTN) that allows simultaneous ablation of the entire renal artery. 39 ...

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