Multicenter prospective study included 2688 patients with a mean age of 81.4 years and 20.5 EuroScore. The all-cause mortality at 2 years was 27.7% (31.5% SOURCE study). The incidence of stroke at 2 years was 7.7% and moderate to severe aortic regurgitation 7.3% and 0.2% respectively. There was a significant improvement in functional class and…
NOBORI II: Final 5-year results of drug-eluting stent with bio-absorbable polymer
This study evaluated the performance of Nobori biolimus bio-absorbable polymer stent in real-world patients. A total of 3067 consecutive patients followed up to 5 years were included. The rate of target lesion (composite of cardiac death, myocardial infarction and target lesion revascularization) was 3.9% at one year and 5.1% at 2 years. Long-term clinical performance…
TRYTON dedicated bifurcation stent in left main coronary artery
TRYTON is a cobalt chromium device specifically dedicated for bifurcation lesions to be implanted in the side branch. Circumflex artery is the major lateral branch fund the coronary tree. Between 2008 and 2011 this work included 52 patients with left main coronary unprotected lesions who underwent angioplasty with drug-eluting stent in the coronary trunk left…
POST -IT: The FFR modifies strategy in almost half of patients
The use of FFR to guide treatment showed improved outcomes in previous studies. However, there are few data on the routine use of the method and its impact on modifying therapeutic decisions for injury and by patient. The aim of this study was to evaluate the routine use of FFR in the real world. All…
DISCOVER Trial: Results at one year of the new nonmetallic percutaneous aortic valve
Direct Flow Medical prosthesis is a nonmetallic, repositionable, recaptured valve (even after posts dilate), that does not require a pacemakers use during both implantation and post-dilatation. The aim of this study was to evaluate new valve results to one year in patients with symptomatic severe aortic stenosis with 19 and 26 mm ring, EuroScore of…
UK TAVI Registry: Long-term results of TAVI in the UK
This record has been created in order to evaluate the results of percutaneous aortic valve replacement in the UK and currently includes more than 4500 patients with 100% follow-up for mortality. The 3-year mortality was 61.6 % beyond the device or path. Atrial fibrillation, renal failure, chronic obstructive pulmonary disease and a EuroSCORE > 18.5…
REDUCE-HTN: safety and efficacy of new bipolar device for renal denervation
This study included 146 patients with resistant hypertension who were medicated with an average of 5.4 drugs. Preliminary 18-month data showed a significant reduction of blood pressure values
Safety and efficacy of a new multi-electrode device for simultaneous renal ablation
This study aimed to establish the safety and effectiveness of renal denervation using the new multielectrode device (EnligHTN) that allows simultaneous ablation of the entire renal artery. 39 patients with resistant hypertension to multiple drugs were included. Procedure was successfully performed in all patients, and no serious adverse events were observed. At 6 months, a…
ADVANCE II: Low incidence of permanent pacemaker for self -expandable valve
The incidence of permanent pacemaker implantation (PPM) is variable between the different series within 30 days of the aortic valve implantation with the CoreValve prosthesis. The aim of this study was to investigate the conduction abnormalities and PPM according to the Conduction Disorders Guide. This multicentre prospective study with a follow-up to 7 days, 30…
TITAN-AMI: Final results of bio-active coated stent
Previous studies suggest the excellent performance of the bioactive coated stent TITAN 2 compared with drug-eluting stents (DES). The aim of the study was to evaluate the results of this device in patients undergoing both ST segment elevation and without ST segment elevation acute coronary syndrome. A total of 1066 patients were included, of whom…
SIMPLICITY HTN -3: subgroup analysis identifies potential confounders
Initial studies showed a blood pressure significant reduction to 3 years in patients with resistant hypertension, while the SIMPLICITY HTN -3 with a larger number of patients compared to a group with “Sham” procedure (renal angiography with conscious sedation) could not confirm the results. The aim of this study was to evaluate the possible confounding…