Courtesy of Dr. José Álvarez ‘Slow flow’ may complicate a rotational atherectomy procedure, especially when done on severely and extensively calcified lesions and small caliber vessels. Although its incidence is between 3% and 27%, its cause remains unclear, and it is thought that platelet antiaggregation induced by burr rotation speed may be behind it. …
Effects of switching from prasugrel to ticagrelor in patients with ACS
Original Title: Pharmacodynamic Effects of Switching from Prasugrel to Ticagrelor Results of the Prospective, Randomized SWAP-3 Study Reference: J Am Coll Cardiol Intv. 2016;() Epub ahead of print. Courtesy of Dr. Agustín Vecchia. At present, the pharmacodynamic effects of switching from prasugrel to ticagrelor in patients under dual APT remain unknown. The present prospective, randomized,…
Different Thienopyridine Loading Strategies to Get the Fastest Effect
Original Title: Randomized Comparison of Different Thienopyridine Loading Strategies in Patients Undergoing Elective Coronary Intervention. The Excelsior LOAD Trial. Reference: Willibald Hochholzer et al. J Am Coll Cardiol Intv. 2016, online before print. This study assesses how to provide a more rapid antiaggregant effect. It compares the effect of a prasugrel load vs. a 600…