This research was designed to test the superiority of plug-based vs. suture-based vascular closure devices in large arteriotomies, such as transcatheter aortic valve replacement (TAVR). Vascular complications from TAVR are relevant and, in many cases, derive from problems with the closure device. The MASH (MANTA vs. Suture-based vascular closure after transcatheter aortic valve replacement) study…