From the total of 1900 patients in the FREEDOM study, 1248 did not require insulin (631 received angioplasty and 617 received CABG) and 602 if required (325 received angioplasty and 277 received CABG). Insulin dependent patients were more obese, with higher glycosylated hemoglobin, increased incidence of heart failure and increased incidence of acute coronary syndromes. Insulin dependent patients showed generally more cardiovascular events (29% versus 19% p <0.5). Both groups had more events with angioplasty than with surgery except those with stroke that were higher with surgery. In the SYNTAX subgroup the score under the angioplasty and surgery was similar.
George D Dangas
2013-10-31
Original title: FREEDOM: A Prospective, Randomized Trial of First Generation Drug-Eluting Stents vs. CABG in Insulin- and Noninsulin-Treated Diabetic Patients
