Review: Two hundred twenty-four patients in a surgical plan, (coronary artery bypass grafting or valve), were randomized to cardiac surgery alone or associated with atrial ablation, (MAZE, 97% for cryoablation). The primary objective was the evaluation of sinus rhythm at 1 year by performing a Holter. The difference was 60.2% versus 35.5% in favor of the MAZE group, (p = 0.002), without thereby increasing preoperative risks or clinical differences between the two groups. This is a study that raised the safety and efficacy criteria in a relatively short period, (one year). Monitoring these patients in the long term and / or designing a trial with these characteristics will reveal the true impact of this strategy.
Petr Widimsky
2012-08-27
Original title: PRAGUE-12: Randomized open multicenter study comparing cardiac surgery with MAZE versus cardiac surgery without MAZE in patients with coronary and/or valvular heart disease and with atrial fibrillation
