Resynchronization therapy is not beneficial in patients with heart failure and narrow QRS

Resynchronization therapy has shown benefits reducing morbidity and mortality in patients with heart failure and wide QRS. Many heart failure patients have mechanical dyssynchrony and this could be improved by resynchronization. The use of resynchronization “off label” in observational studies and small randomized studies raised up the need for a larger work to vouch this practice.

The aim of this study was to evaluate the effects on morbidity and mortality of Cardiac Resynchronization Therapy Defibrillators (CRT-Ds) implantation in patients with moderate to severe impairment of left ventricular systolic function, narrow QRS (

Conclusion:

The implantation of a Cardiac Resynchronization Therapy Defibrillators (CRT-Ds) in patients with heart failure and narrow QRS and dyssynchrony by echocardiography does not improve the primary efficacy and may increase mortality.

Read editorial

Read editorial

Johannes%20Holzmeister_slides
Johannes Holzmeister
2013-09-03

Original title: Cardiac-Resynchronization Therapy in Heart Failure with a Narrow QRS Complex.

More articles by this author

ATOMIC: Omecamtiv Mecarbil does not relieve dyspnea in patients with heart failure

This is a phase 2 randomized, double-blind controlled study to test the effect of omecamtiv mecarbil on progressive doses in patients with dyspnoea and...

AQUARIUS: Aliskiren, without impact on the progression of atherosclerosis

This double-blind, multicenter randomized study compared aliskiren versus placebo in 613 patients with coronary artery disease and systolic blood pressure between 125 and 139...

BIC 8: Copetin associated with troponin can rule out acute myocardial infarction in the emergency room.

The acute chest pain is responsible for more than 11 % of queries to an emergency service . Only 10% of these patients really...

Group Tour of France: good news for cyclists.

The benefits of regular physical activity are well established, but there are some controversies related to the potential harmful physical activity of high competition....

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Related Articles

SOLACI Sessionsspot_img

Recent Articles

TricValve Transcatheter Bicaval Valve System for Severe Tricuspid Insufficiency: Events at One Year

TricValve is the first bicaval valve system to obtain CE-Mark approval. This device heterotopic device eliminates tricuspid insufficiency reflux into the venous system, reducing...

Long Term Results of the International Chimney Registry

The International Chimney Registry was an observational study aimed at assessing the use of chimney stenting during TAVR either to predict or treat coronary...

CANNULATE TAVR extended study: Impact of Commissural and Coronary Alignment in Coronary Cannulation Following TAVR with Evolut Fx

The new valve Evolut FX has shown better commissural alignment vs. its predecessor Evolut Pro+. Prior studies have already shown commissure alignment facilitates post...