EuroPCR 2023 | EBC Two – Provisional Stenting vs Culotte in Bifurcations

MD Sandeep Arunothayaraj presented the 5-year followup of EBC Two (which had not previously shown significant differences in clinical outcomes at 12 months) in patients randomized to provisional stenting vs. systematic culotte in bifurcations that were not left main. 

 

The study followed up 200 patients with true bifurcations, side branch ≥2.5mm and lesion length ≥5mm, treated with second generation drug eluting stents. Primary end point was the composite of mortality, myocardial infarction or target vessel revascularization. 

Mean age was 63 and the main localization was the anterior descending and first diagonal branch (77.7%). Mean branch diameter was 2.7±0.3mm, with lesion length 10.3±7.2mm at 5 years. 

Primary end point happened in 18.4% of cases treated with provisional stenting and 23.7% of patients treated with systematic culotte (HR 0.75, CI 95% 0.41-1.38). There were no significant differences.

When looking at bifurcation related adverse cardiovascular events (BACE – acute vessel occlusion, stent thrombosis, AMI type 4 or new revascularization) there were no significant differences (5.8% vs 7.2%, HR 0.80, CI 95% 0.27-2.39; P=0.69).

Read also: Cobertura EuroPCR 2023.

Routine use of culotte did not improve MACE at 5 years, vs. provisional stenting (only 16% of patients using this strategy required side branch stenting).

Dr. Omar Tupayachi

Dr. Omar Tupayachi.
Member of the Editorial Board of SOLACI.org.

Reference: Presented by Sandeep Arunothayaraj in Late Breaking Trials Sessions, EuroPCR 2023, May 16, 2023, París, France.


Subscribe to our weekly newsletter

Get the latest scientific articles on interventional cardiology

More articles by this author

Patients at High Risk of Bleeding After Coronary Angioplasty: Are Risk Assessment Tools ARC-HBR and PRECISE-DAPT Useful?

Patients undergoing coronary stenting typically receive dual antiplatelet therapy (DAPT) for 6 to 12 months, consisting of a P2Y12 receptor inhibitor and aspirin. While DAPT...

ACC 2025 | WARRIOR: Ischemia in Women with Non-Obstructive Coronary Artery Disease

Approximately half of all women with symptomatic ischemia who undergo coronary angiography are found to have non-obstructive coronary artery disease ((ischemia and non-obstructive coronary...

ACC 2025 | FLAVOUR II: Angiography-Derived FFR-Guided vs. IVUS-Guided PCI

Physiological assessment is effective when it comes to decision-making for percutaneous coronary intervention (PCI). However, despite the available evidence, its use remains limited. AngioFFR...

ACC-2025 Congress Second Day Key Studies

BHF PROTECT-TAVI (Kharbanda RK, Kennedy J, Dodd M, et al.)The largest randomized  trial carried out across 33 UK centers between 2020 and 2024, assessing...

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Related Articles

SOLACI Sessionsspot_img

Recent Articles

TAVR in Small Annuli: What Valve Should We Use?

One of the major challenges of severe aortic stenosis are patients with small aortic annuli, defined as ≤430 mm² aortic valve area. This condition...

Patients at High Risk of Bleeding After Coronary Angioplasty: Are Risk Assessment Tools ARC-HBR and PRECISE-DAPT Useful?

Patients undergoing coronary stenting typically receive dual antiplatelet therapy (DAPT) for 6 to 12 months, consisting of a P2Y12 receptor inhibitor and aspirin. While DAPT...

ACC 2025 | WARRIOR: Ischemia in Women with Non-Obstructive Coronary Artery Disease

Approximately half of all women with symptomatic ischemia who undergo coronary angiography are found to have non-obstructive coronary artery disease ((ischemia and non-obstructive coronary...