Women are underrepresented in numerous percutaneous transluminal coronary angioplasty (PTCA) studies, particularly in those analyzing calcified or high-risk lesions. This leads to worse clinical outcomes for this group.

Researchers conducted an analysis on 389 women with severely calcified coronary lesions who were treated with coronary lithotripsy.
The average age was 73 years; 46% of subjects had diabetes, 32% had a history of myocardial infarction, 38% had undergone prior PTCA, and 28% had impaired renal function.
Additionally, 46% had stable coronary syndrome, 24% had non-ST-elevation myocardial infarction (NSTEMI), while unstable angina and ST-elevation myocardial infarction (STEMI) were less frequent.
At 30 days, cardiac mortality was 1.3%, the infarction rate was 10.6%, and the target lesion revascularization (TLR) rate was 1.3%. There was a significant improvement in quality of life.
Presented by Margaret McEntergart during EuroPCR 2025 in Paris, France.
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