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ESC 2012.

Summary of the presentations, original articles and major slides shown at an event which was, without question, an academic calendar marker, held in Munich from the 25th to 29th August 2012.

TRILOGY-ACS: Prasugrel vs. Clopidogrel in ACS without ST segment elevation in patients to be treated medically without revascularization.
 TRILOGY-ACS: Prasugrel vs. Clopidogrel in ACS without ST segment elevation in patients to be treated medically without revascularization. Read article Magnus Ohman 2012-08-25 ...

PURE: This study shows different patterns of cardiovascular risk factor prevalence in countries with different socio-economical background, and recommends individualized intervention..
Presentation Summary: The Prospective Urban Rural Epidemiologic (PURE) study evaluated 153996 people from different countries and different socioeconomic background. Tobacco consumption, physical ...

ALTITUDE: Aliskiren Trial In Type 2 Diabetes Using Cardio Renal Endpoints.
Editorial Comment: Morbimortality in diabetic patients is still a matter of deep concern in the context of reduced cardiovascular mortality of recent years. Based on the proven clinical benefit of ...

PARAMOUNT: Promising results of double action drug treatment for patients with heart failure and preserved ejection fraction .
Editorial Comment: This Phase II study included 149 patients following these criteria: NYHA II-IV heart failure, +40 yr, LVEF ≥ 45% NT-proBNP> 400 pg/ml. The study aimed at reducing NT-proBNP ...

Aldo-DHF: Aldosterone Receptor Blockade in Diastolic Heart Failure Treatment
Editorial Comment: Fifty per cent of all HF patients involves Diastolic Heart Failure or HF with conserved ventricular function. This study aimed at evaluating the efficacy and safety of 25mg ...

DeFACTO: Diagnostic Precision of CT Angiography in Determining FFR.
 DeFACTO: Diagnostic Precision of CT Angiography in Determining FFR.  Read article James K. Min 2012-08-25 ...

PROTECT: A comparison of thrombosis incidence between the drug-eluting stents sirolimus and zotarolimus.
Summary: Randomized, open, pragmatic essay PROTECT (patient related outcomes of Endeavor versus Cypher stenting trial) compared two drug-eluting stents with different behaviors, (Cypher ® and ...

IABP-SHOCK II: Intra-aortic balloon use impact on 30-day mortality in patients with cardiogenic shock.
 IABP-SHOCK II: Intra-aortic balloon use impact on 30-day mortality in patients with cardiogenic shock.  Holger Thiele 2012-08-26 Original title:  IABP-SHOCK II: Randomized ...

FAST MI: AMI improved the survival associated with the clinical characteristics changes of patients in the French National Registry.
Presentation Summary: The French National Registry included patients admitted with acute myocardial infarction between 1995 and 2010 (n = 6707). Over time, authors noted a reduction in the age of ...

GARY: German Aortic Valve Registry.
Presentation Summary: The German Aortic Stenosis Registry collected data from German centers. 13,860 patients who were undergoing valve replacement surgery or percutaneous valve implant in 2011 were ...

GRACE: Use of insulin glargine and fatty acids to reduce atherosclerosis progression.
Presentation Summary: There is a clear association between hyperglycemia and the development of atherosclerosis. The GRACE sub trial, (from ORIGIN study), evaluated the administration of omega-3 and ...

ACCESS-EUROPE: 12 months results in percutaneous treatment of mitral insufficiency .
Presentation Summary: ACCESS-EUROPE multicenter registry included 567 patients with severe mitral regurgitation treated with Mitral Clip in 14 European centers. Procedural success was high, (99.6%), ...

PRAGUE-12: Surgical Atrial Ablation: Follow the one-year results.
Review: Two hundred twenty-four patients in a surgical plan, (coronary artery bypass grafting or valve), were randomized to cardiac surgery alone or associated with atrial ablation, (MAZE, 97% for ...

AFIB ABLATION PILOT: Ablation of Atrial Fibrillation by Radiofrequency.
Review: A European multicenter registry, (mainly in France, Italy and Germany), which included 1,410 patients - evidence of real-world - in which ablation performed by radiofrequency had a success ...

CORE 320: Diagnostic performance of coronary angiotomography including evaluation of myocardial perfusion versus isolated anatomical assessment.
Review: The CORE-320 multicenter study compared combined angiotomography assessments: anatomical (coronary) and functional (myocardial perfusion) versus anatomical only. For this study, 381 patients ...

WOEST: Randomized trial that compared dual therapy versus triple therapy on anticoagulated patients.
A multicenter randomized study, (n = 573), that evaluated the role of aspirin in anticoagulated patients undergoing angioplasty. The primary endpoint was the rate of total bleeding, (TIMI), at 12 ...

JAPAN EQ: Cardiovascular risk after natural disasters.
Natural disasters have been associated with an increase in cardiovascular mortality. In the Miyagi area, near the epicenter of an earthquake and tsunami in 2011, we analyzed the number of ...

FAME II: Ischemia guided (IG) percutaneous coronary intervention (PCI) is superior to medical treatment.
Review: Stable coronary disease remains a scenario where percutaneous coronary intervention, (PCI), has not cleared the edges. In a study conducted in 28 centers in Europe and the United States, a ...

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