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Coronary flow reserve is associated to adverse events regardless angiographic severity.

This study included 329 consecutive patients derived to coronary angiography based on myocardial perfusion tests or PET...
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ITALIC PLUS: 6 months of double antiaggregation for no less than 24 months

Article This multicenter study included patients receiving the second generation stent XIENCE V (Abbott Vascular) randomized to 6...
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DAPT TRIAL: double antiaggregation remains controversial

Article This multicenter randomized control study with placebo was designed to determine the risks and benefits of double...
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ISAR-SAFE: 6 vs. 12 month clopidogrel administration after DES implantation

The aim of this randomized double blind control trial was to validate the safety and efficacy of...
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Reduction of ischemic events after 30 months of prasugrel following TAXUS stent implantation

Article The TAXUS Liberté Post Approval study included patients treated with TAXUS paclitaxel DES receiving prasugrel for 12...
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Day 2

IMPROVE-IT Trial: Finally the association of ezetimibe and simvastatin reduces events vs. simvastatin monotherapy

This is a multicenter, randomized, double blind study designed to test the hypothesis that the combination of...
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FACTOR 64: Routine coronary CT angiography in patients at high risk for heart disease.

Article 900 patients with asymptomatic diabetes mellitus were randomized to CT angiography vs. Standard management. Primary end point...
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ODYSSEY ALTERNATIVE: Monoclonal antibody alirocumab vs. ezetimibe in patients with statin intolerance

Statin intolerance limits patients’ capacity to reach their LDL goals. This study compared the new drug alirocumab...
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