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GIPS -III: Metformin does not improve ejection fraction in non-diabetic patients undergoing primary angioplasty

There are experimental studies suggesting that metformin admin before and during ischemia and reperfusion could help to...
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HEAT PPCI: Bivalirudin raises major cardiac events and does not reduce bleeding. The most controversial and criticized study at the ACC 14.

This randomized trial of a single center with consent obtained after randomization compared the use of bivalirudin...
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CORP-2 Trial: Colchicine effective in reducing the recurrence of pericarditis associated withconventional anti-inflammatory pattern.

Colchicine is effective in treating an acute pericarditis event and initial recurrences;however, there is no conclusive data...
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Melody

The ducts of the right ventricle to the pulmonary artery are used in approximately 20 % of...
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Negative ultrasensitive troponin T values may help discriminate patients with chest pain in the emergency

New laboratory tests can detect minimally elevated  levels few hours before regarding detection methodologies of previous generations.The...
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LAPLACE 2: Evolocumab effective in reducing LDL associated with statins

There are several patients who do not reach recommended LDL cholesterol despite maximally tolerated doses of statins...
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MADIT -CRT: Increased survival with resynchronization therapy plus defibrillator in patients with mild heart failure.

The MADIT -CRT study (Multicenter Automatic Defibrillator Implantation with Cardiac Resynchronization Therapy) had shown that early intervention...
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Global Registry SYMPLICITY demonstrated the safety of renal denervation system

The Global SYMPLICITY registry is a prospective, multicenter study sponsored by Medtronic to evaluate long- term renal...
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