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Coronary disease

TCT 2025 | NOBLE: 10-Year Outcomes of Percutaneous Coronary Intervention Versus Surgery in Unprotected Left Main Coronary Artery Disease

Unprotected left main coronary artery (LMCA) disease remains one of the most severe forms of coronary artery...
Dr. Juan Manuel Pérez -
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Coronary Disease

TCT 2025 | IRONMAN II Study: Sirolimus-Eluting Iron Bioresorbable Stent in Coronary Artery Disease

Bioresorbable coronary stents represent a step toward strategies without permanent metallic implants, although the first polymer-based platforms...
Dr. Juan Manuel Pérez -
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Structural heart disease

TCT 2025 | PREVUE-VALVE: Prevalence of Valvular Heart Disease in Elderly US Patients

The PREVUE-VALVE study was designed to determine the true prevalence and demographic determinants of valvular heart disease...
Dr. Juan Manuel Pérez -
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Mitral valve

TCT 2025 | Transcatheter Mitral Valve Replacement with SAPIEN M3: ENCIRCLE 1-Year Outcomes

Transcatheter mitral valve replacement (TMVR) is an emerging option for patients with symptomatic mitral regurgitation (MR) who...
Dr. Juan Manuel Pérez -
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Structural heart disease

TCT 2025 | PARTNER 3 Trial 7-Year Outcomes: TAVR vs SAVR in Low-Risk Patients

The randomized PARTNER 3, which initially showed TAVR superiority when using the SAPIEN 3 valve over SAVR...
Dr. Juan Manuel Pérez -
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Acute coronary syndromes

TCT 2025 | VICTORY Trial: super-high-pressure NC balloon vs. IVL in severely calcified coronary lesions

Recent studies such as ECLIPSE have demonstrated the safety of non-compliant (NC) balloons compared with orbital atherectomy,...
Dr. Omar Tupayachi -
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Calcified Lesions

TCT 2025 | ShortCUT Trial: intravascular lithotripsy vs. cutting balloon in calcified coronary lesions

Coronary calcification is a major determinant of PCI complexity and failure. Balloon-based plaque-modifying devices —such as cutting...
Dr. Omar Tupayachi -
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Acute coronary syndromes

TCT 2025 | SELUTION4ISR: sirolimus-eluting balloon for in-stent restenosis

In-stent restenosis (ISR) continues to be a relevant clinical challenge in contemporary PCI practice. In the DES...
Dr. Omar Tupayachi -
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