Original title: Access Site Complications After Peripheral Vascular Interventions. Incidence, Predictors, and Outcomes. Reference: Daniel Ortiz et al. Circ Cardiovasc Interv. 2014 Nov 11. Epub ahead of print. Hematomas and pseudoaneurysms are the most common complications of peripheral angioplasty, though its incidence and risk factors are unclear. A retrospective analysis was performed in 22226 patients receiving peripheral…
Renal angioplasty versus medical treatment, no clinical benefit and only a modest help to control blood pressure
Original title: Stenting and Medical Therapy for Atherosclerotic Renal-Artery Stenosis. CORAL trial. Reference: Christopher J. Cooper et al. DOI: 10.1056/NEJMoa1310753 Between 1 and 5% of the hypertensive population has renal artery stenosis and in general, this is combined with peripheral and coronary vascular disease. The renal artery stenosis may result in hypertension, ischemic nephropathy, and multiple long-term…
Cardiac baroreflex sensitivity can predict response to renal denervation
Original title: Impaired Cardiac Baroreflex Sensitivity Predicts Response to Renal Sympathetic Denervation in Patients with Resistant Hypertension. Reference: Christine S. Zuern et al. J Am Coll Cardiol, article in press. Renal denervation is a new treatment option for patients with resistant arterial hypertension and it is assumed to reduce efferent renal and central sympathetic activity. Given the multifactorial…
Renal denervation for moderate resistant hypertension
Original title: Renal denervation in moderate treatment resistant hypertension. Reference: Christian Ott et al. J Am Coll Cardiol 2013. Article in press. Symplicity trials HTN1 and HTN 2 demonstrated that renal denervation is apparently safe in patients with severe resistant hypertension, (≥ 160 mm Hg despite ≥ 3 drugs including a diuretic). This cut of more than 160…
Renal Denervation: All Published Literature Available so far
Original title: Effectiveness of Renal Denervation Therapy for Resistant Hypertension: A Systematic Review and Meta-Analysis. Reference: Mark I. Davis et al. J Am Coll Cardiol 2013. Article in press. Resistant Hypertension is the impossibility to control blood pressure despite the use of 3 or more different types of drugs, including diuretics. For most studies, at least 10 to…
Renal denervation at one year, the benefit remains.
Original title: Renal Sympathetic Denervation for Treatment of Drug-Resistant Hypertension Clinical Perspective Reference: Murray D. Ester et al. Circulation 2012; 126: 2976-2982 Renal sympathetic activation contributes to the pathogenesis of hypertension. The Symplicity HTN – 2 was a multicenter, randomized study which demonstrated that renal denervation produced a significant decrease in blood pressure at 6 months in patients…
Renal Denervation: a strategy that has come to stay?
Our editors talked with Dr. Marco Wainstein, an active member of SOLACI Web Editorial Board SOLACI WEB: Which is the rationale for renal denervation? Marco Wainstein, MD: The rationale for renal denervation is based on the modification of the sympathetic innervation of the renal arteries affecting both afferent and efferent nerves. Ultimately, renal denervation would…