Despite optimal medical treatment and modification of risk factors, patients may spend long periods without symptoms and then experience acute coronary syndrome without any prior indication that may allow us to predict the time of occurrence.
This is why the possibility of detecting patients with vulnerable plaques and who are at higher risk is very important.
Near-infrared spectroscopy (NIRS) is available with a dual catheter for intravascular ultrasound (IVUS).
This study included 1563 patients with suspected coronary disease. NIRS-IVUS imaging was performed in two or more arteries, and patient- and artery-level analyses were carried out.
As regards the patient-level analysis, the risk of experiencing an event within 24 months for each 100-unit increase in maxLCBI4mm (lipid load index by NIRS) was 18%. The risk was 12.6% higher with maxLCBI4mm ≥400, compared with 6.3% for patients with maxLCBI4mm <400.
NIRS seems to be far from clinical practice, but it may help with the detection of non-culprit plaque or in patients who are at high risk of developing it in the future.
Original title: LRP (LIPID RICH PLAQUE STUDY) Assessment of Coronary Near-Infrared Spectroscopy Imaging to Detect Vulnerable Plaques and Vulnerable Patients.
Presenter: Ron Waksman.
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