EVOLVE II: Diabetes Substudy: Results at 3 Years after the SYNERGY Stent in Diabetics

Courtesy of SBHCI

EVOLVE II: Diabetes Substudy: Results at 3 Years after the SYNERGY Stent in DiabeticsDiabetic patients have worse evolution after coronary PCI. Drug eluting stents with bioresorbable polymers were designed to facilitate arterial healing, and reduce inflammation and late and very late thrombosis risk.

 

This sub-study of diabetic EVOLVE II patients presents the 3 year outcomes of the SYNERGY stent.

 

The EVOLVE II included 1684 patients with ≤3 lesions in one or two native arteries with a lesion length of ≤34 mm and a reference diameter of ≥2.25 mm and ≤ 4.0 (the study excluded left main, CTO, vein grafts, instent restenosis and ST elevation MI).

 

Of the total number of patients, 846 received the SYNERGY stent, and 838 the PROMUS Element Plus stent.

Primary end point (cardiovascular death, vessel related MI, and target vessel revascularization) saw a 12.2% incidence in diabetic patients, which is comparable to the 10.8% of the general population, despite 30% of diabetic patients were insulin-dependent.

 

It is worth mentioning that 44% of diabetic patients were still on antiaggregants at 3 year follow up.

 

Conclusion

The 3 year outcomes reinforce the evidence in favor of the use of the SYNERGY stent in diabetic patients.

 

Courtesy of la SBHCI

 

Dra. Martine Gilard
Dra. Martine Gilard

Original Title: Outcomes after PCI with a bioresorbable polymer- coated, everolimus-eluting coronary stent in patients with diabetes: three-year results from the EVOLVE II Diabetes Substudy.

Presenter: Martine Gilard.

 

 

Loading...


Subscribe to our weekly newsletter

Get the latest scientific articles on interventional cardiology

We are interested in your opinion. Please, leave your comments, thoughts, questions, etc., below. They will be most welcome.

More articles by this author

Spontaneous Left Main Dissection: Clinical Characteristics, management and Outcomes

Courtesy of Dr. Juan Manuel Pérez. Spontaneous left main dissection in an uncommon, and potentially life-threatening, cause of acute MI. The aim of this study,...

Pretreatment with DAPT in Acute Coronary Syndrome: An Ongoing Debate?

In acute coronary syndrome (ACS) dual antiplatelet therapy (DAPT) has become a fundamental pillar after percutaneous coronary intervention (PCI), preventing stent thrombosis and acute...

Another Blow for Intra-Aortic Balloon Pumo Counterpulsation? Randomized Study on Its Use in Chronic Heart Failure Progressing to Cardiogenic Shock

Cardiogenic shock (CS) remains a condition with extremely high mortality (around 50%). While most therapies for this pathology have been studied in CS secondary...

Radial Patency in Coronary Procedures: Is Heparin Enough or Should We Aim for Distal Transradial Access?

Transradial access is the preferred route in most coronary procedures due to its proven reduction in mortality compared to transfemoral access. However, one of...

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Related Articles

SOLACI Sessionsspot_img

Recent Articles

Spontaneous Left Main Dissection: Clinical Characteristics, management and Outcomes

Courtesy of Dr. Juan Manuel Pérez. Spontaneous left main dissection in an uncommon, and potentially life-threatening, cause of acute MI. The aim of this study,...

Pretreatment with DAPT in Acute Coronary Syndrome: An Ongoing Debate?

In acute coronary syndrome (ACS) dual antiplatelet therapy (DAPT) has become a fundamental pillar after percutaneous coronary intervention (PCI), preventing stent thrombosis and acute...

Measuring Post-TAVI Gradients and Their Implications: Are Invasive and Echocardiographic Assessments Comparable?

Transcatheter aortic valve implantation (TAVI) is considered the treatment of choice for a significant proportion of patients with symptomatic aortic stenosis. Outcomes have improved...