Fenestrated Endografts as Treatment for Type I Endoleak: What is the Price of Success?

Both fenestrated and branched endografts are effective to treat patients after failure of their initial endograft due to significant type I endoleak. This situation is costly both because of the devices themselves, and also due to the several endovascular and surgical procedures required.

Prótesis fenestradas para tratar endoleak tipo 1 ¿cuál es el precio del éxito?

Failure of an endograft to treat an infrarenal abdominal aortic aneurysm due to the development of a type Ia endoleak exposes patients to pressurization of the sac, which may cause a rupture. Type I endoleaks must undoubtedly be treated—unlike type II endoleaks, around which controversy may arise.

The purpose of this study was to evaluate the results of fenestrated/branched grafts for the treatment of type Ia endoleaks.

Between 2010 and 2019, 85 consecutive patients who received a fenestrated/branched graft after failure of a conventional prosthesis were included. The primary endpoint was freedom from re-intervention and death related to the procedure.

In 30 cases (35%), the initial prosthesis was implanted in a hostile neck—either too short (<10mm) or angled (>60°). Less frequent reasons were poor placement of the initial prosthesis, sizing error, or stent migration. 

Type Ia endoleaks were observed 59 ± 25 months following implantation of the initial prosthesis. As a solution, 82 fenestrated grafts and 3 branched grafts were used. Overall technical success was 94%, with one persistent type Ia endoleak, and two unsuccessful stent graft implantations.

In-hospital mortality rate was 5%, and the most feared complication in this type of procedure—spinal cord ischemia—occurred in four patients.


Read also: SOLACI PERIPHERAL | Type Ib Endoleak Correction in Patient After Minimally Invasive Hybrid Treatment in Type A Aortic Disection.


At three years, the survival rate was 64% with an overall freedom from any re-intervention or aneurysm-related death of 40%. However, the secondary patency rate of the target visceral arteries was 96%.

Despite all efforts, six patients had to undergo conventional surgery.

Conclusion

Fenestrated/branched grafts are an effective treatment when conventional prostheses fail due to type 1A endoleak, although re-interventions and device costs can be high.

Original title: Prospective Multicentre Cohort Study of Fenestrated and Branched Endografts After Failed Endovascular Infrarenal Aortic Aneurysm Repair with Type Ia Endoleak.

Reference: Aurélien Hostalrich et al. Eur J Vasc Endovasc Surg. 2021 Aug 4;S1078-5884(21)00525-6. Online ahead of print. doi: 10.1016/j.ejvs.2021.06.019. 


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