ACC 2022 | SPYRAL HTN-ON: Is It Time to Start Using Renal Denervation?

Thirty-eight patients were enrolled in the renal denervation (RDN) group, and 42 in the control group. 

ACC 2022

The mean ambulatory systolic blood pressure and the mean ambulatory diastolic blood pressure were significantly lower at 24 and 36 months for patients in the RDN group compared with the control group, despite similar medical treatment with antihypertensive drugs.

Antihypertensive drugs received at 36 months were 2.13 in RDN and 2.55 in the control group (p = 0.24).

At 36 months there was a reduction in systolic pressure of -18.7 mmHg for RDN vs. -8.6 mmHg for the control group (n = 32; adjusted treatment difference -10.0 mm Hg, 95% confidence interval: 16.6 to -3.3; p = 0.0039), as well as a reduction in diastolic pressure of -11 mmHg (-19.8 to -2.1; p = 0.016) and a reduction in morning systolic pressure.

Original Title: Long-term efficacy and safety of renal denervation in the presence of antihypertensive drugs (SPYRAL HTN-ON MED): a randomised, sham-controlled trial.

Dr. Carlos Fava - Consejo Editorial SOLACI

Dr. Carlos Fava.
Member of the editorial board of SOLACI.org .


Subscribe to our weekly newsletter

Get the latest scientific articles on interventional cardiology

More articles by this author

New Carotid PCI All-in-One System

Carotid stenting is equivalent to carotid endarterectomy in terms of major adverse events (death, AMI, and stroke). However, it entails higher risk of minor...

PERFORMANCE II Trial: Safety and Efficacy of the New NeuroGuard Carotid Stent System

The percutaneous treatment of carotid artery disease through stenting (CAS) for the prevention of cerebrovascular disease has proven to be an effective alternative compared...

Trends in the Treatment of Critical Lower Limb Ischemia

Approximately 25% of patients with critical lower limb ischemia (CLLI) face amputation within the first year after diagnosis (according to statistics from the United...

Endovascular Treatment of Iliofemoral Disease for the Improvement of Heart Failure with Preserved Ejection Fraction

Peripheral artery disease (PAD) is a significant risk factor in the development of difficult-to-treat conditions, such as heart failure with preserved ejection fraction (HFpEF)....

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Related Articles

SOLACI Sessionsspot_img

Recent Articles

Unplanned Coronary Angiography After TAVR: Incidence, Predictors, and Outcomes

The importance of assessing coronary artery disease in patients undergoing transcatheter aortic valve replacement (TAVR) is well recognized due to the high prevalence of...

Intravascular Lithotripsy in Calcified Coronary Lesions: Success Predictors

Coronary artery calcification (CAC) is increasingly common in patients undergoing percutaneous coronary intervention (PCI). Intravascular lithotripsy (IVL) has been established as an effective tool...

TAVR Unload: TAVR in Moderate Aortic Stenosis and Ventricular Function Deterioration

Aortic Stenosis (AS) significantly contributes to valvulo-arterial impedance in patients with heart failure and reduced ejection fraction (HFrEF), making it a relevant therapeutic target...