Renal articles


Renal Denervation is Safe and Reduces Blood Pressure and Medication

Renal Denervation is Safe and Reduces Blood Pressure and Medication

We are well aware of the multifactorial nature of hypertension, as well as the fact that it responds well to medication and lifestyle changes.  It can be treated with renal denervation (RDN), which has been shown safe and effective in several randomized and non-randomized studies. However, the group of patients that will benefit most from

Simplified Rapid Intravenous Hydration for the Prevention of Contrast-Induced Nephropathy in Patients with Chronic Kidney Disease

Patients with chronic kidney disease (CKD) undergoing coronary angiography are at increased risk of developing contrast-associated acute kidney injury (CA-AKI), which is associated with increased mortality. According to current guidelines, the standard treatment for preventing CA-AKI in patients with moderate to severe CKD is long-duration peri-procedural intravenous hydration with saline solution. This standard hydration is

EuroPCR 2023 | New Renal Denervation Devices Show Promising Results

The Netrod System study included 205 patients with uncontrolled essential hypertension while taking two drugs (nifedipine and hydrochlorothiazide), who were randomized 2:1 to denervation or sham control. All subjects had undergone renal angiography before randomization. Renal denervation was done using the Setrod System device. Mean patient age was 50 years old, and 16% of subjects were female.

EuroPCR 2023 | More Evidence in Favor of Renal Denervation

This study included 219 patients with uncontrolled essential hypertension who had received at least two antihypertensive drugs. All of them underwent a renal angiography and were randomized to the renal denervation group or the control group. Denervation was performed using the SyMapCath I catheter and the SYMPIONEER S1 generator/stimulator. Mean patient age was 45 years old, and

Una nueva molécula para evitar la nefropatía por contraste

Is There Any Difference in Clinical Outcomes Between Transient and Persistent Acute Kidney Injury in ACS Patients after Invasive Treatment?

Acute kidney injury (AKI) following acute coronary syndrome (ACS) is associated with prolonged hospital stay and worse prognosis at followup. However, serum creatinine level increase can either be transient or permanent. At present, retrospective studies show transient AKI patients present similar survival rate to patients with no AKI. The prognostic implications of transient and persistent


TEATE Trial: Urine Alkalinization as a Target to Prevent Contrast-Associated Kidney Injury

Acute kidney injury related to iodinated contrast significantly increases morbidity and mortality after angiography or angioplasty. According to registries, its prevalence can vary from 2% in low-risk population to up to 50% in high-risk subjects. Its risk factors include previous renal failure, diabetes, age, and the amount/type of contrast used. As a preventive measure, international

TCT 2022

SYMPLICITY HTN-3 Trial. Evolution at 3 Years

The SYMPLICITY 3-year outcomes are out. Bear in mind this is the largest study we have had so far.  It included 535 patients. 364 received renal denervation (RDN) and 171 went to the control group.  At 36-month followup, 101 patients crossed over.  The procedure was safe at 36 months, both for patients receiving it at

TCT 2022

TCT 2022 | RADIANCE II Pivotal Trial

Renal denervation has been developed to treat blood hypertension. Even though at present is still not common, with the development of new technology and improved technique, its results are promising.  The RADIANCE II Pivotal included 224 patients. 150 received renal denervation with ultrasound (uRDN) and 74 went to the control group. Efficacy primary end point

¿Se debe tener en cuenta el género para revascularizar el tronco?

Gender Differences and 10-Year Prognosis in STEMI

Coronary artery disease in women usually develops 10 years later than in men, and some evidence suggests women have higher mortality, especially when it comes to ST elevation MI (STEMI). Registries have shown higher mortality both in hospital and at one year follow up.  In part, this difference is observed because of the gap in


RADIANCE-HTN SOLO: Control Durability of BP

In patients with hard-to-control high blood pressure (HBP), both non-pharmacological treatment and lifestyle changes have been useful to improve its control. Renal denevartion (RDN) was assessed as part of this complementary treatment, since some research has shown that this alternative decreases blood pressure (BP) values in different groups treated with either radiofrequency or ultrasound (uRDN).


Renal Guard System to Prevent Contrast Induced Acute Kidney Injury in Patients at High Risk Contrast Induced Acute Kidney Injury

Contrast Induced Acute Kidney Injury (CI-AKI) is associated to increased costs and unfavorable results after hemodynamic procedures. Its incidence ranges between 2% and 7% according to the most recent literature.  Multiple protection strategies have been analyzed in randomized studies, but no therapy has shown clear benefits. The RenalGuard (RG) is a device that uses furosemide-induced diuresis with