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ENGAGE AF-TIMI 48: Endoxaban versus warfarin in atrial fibrillation

The endoxaban is an oral direct inhibitor of factor Xa with a rapid onset of action and...

EU-PACT: Warfarin dose guided by genotype

Anticoagulation level in response to a fixed dose of warfarin is difficult to predict at the start...

RADAR AF: High-frequency ablation versus pulmonary vein isolation to treat atrial fibrillation

Atrial fibrillation is initiated by focal triggers and maintained by an atrial substrate called fractioned complex of...

ERASE: Endovascular treatment plus exercise versus exercise alone to treat claudication

Initial therapy for intermittent claudication has been historically the gear train, however, especially in recent years; the...

NIAMI: Nitroprusside infusion prior to primary angioplasty

The phenomenon of reperfusion injury is responsible for 50 % of the final infarct size. Several pharmacological...

TTM: Hypothermia after cardiac arrest does not offer benefits

Previous studies evaluated therapeutic hypothermia (32 ° C to 34 ° C for 12-24 hours) in patients...

Mild hypothermia in pre-hospital phase after cardiac arrest

Hypothermia in the hospital phase at 32-34 ° C improves neurological outcome in patients resuscitated after ventricular...

Promoting cardiovascular health in the preschool age

Cardiovascular disease is the worldwide leading cause of death. Changes in lifestyle, diet and sedentary routine have...