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PARAMOUNT: Promising results of double action drug treatment for patients with heart failure and preserved ejection fraction .

Editorial Comment: This Phase II study included 149 patients following these criteria: NYHA II-IV heart failure, +40...

ALTITUDE: Aliskiren Trial In Type 2 Diabetes Using Cardio Renal Endpoints.

Editorial Comment: Morbimortality in diabetic patients is still a matter of deep concern in the context of...

PURE: This study shows different patterns of cardiovascular risk factor prevalence in countries with different socio-economical background, and recommends individualized intervention..

Presentation Summary: The Prospective Urban Rural Epidemiologic (PURE) study evaluated 153996 people from different countries and different...

POSEIDON study: A prospective, randomized, single-center study comparing a sliding-scale hydration strategy for the prevention of contrast-induced nephropathy.

Background: Contrast-induced nephropathy has been the subject of many studies not only because of the morbidity associated...

PC Trial: Clinical treatment or closure of patent foramen oval in cryptogenic stroke patients?

Background: The association between paradoxical embolism, including cryptogenic stroke, and the presence of patent foramen oval (PFO)...

RESPECT: Randomized clinical trial evaluated the patent foramen oval closure vs clinical treatment in patients with cryptogenic stroke

Fundamentals: Etiology of cryptogenic stroke stills a major challenge for medicine. Paradoxical embolism remains one of the...

ADAPT-DES: Results at 1 year of the clinical impact of hypo-responders to aspirin and clopidogrel.

Background: The ADAPT-DES registry showed a strong correlation between hypo-responders to clopidogrel and the likelihood of stent...

POST trial: Post-conditioning effect in myocardial reperfusion with primary angioplasty.

Ischemic postconditioning obtained through reversible ischemia and reproduced during reperfusion after a prolonged ischemic injury has shown...