Resynchronization therapy is not beneficial in patients with heart failure and narrow QRS

Resynchronization therapy has shown benefits reducing morbidity and mortality in patients with heart failure and wide QRS. Many heart failure patients have mechanical dyssynchrony and this could be improved by resynchronization. The use of resynchronization “off label” in observational studies and small randomized studies raised up the need for a larger work to vouch this practice.

The aim of this study was to evaluate the effects on morbidity and mortality of Cardiac Resynchronization Therapy Defibrillators (CRT-Ds) implantation in patients with moderate to severe impairment of left ventricular systolic function, narrow QRS (

Conclusion:

The implantation of a Cardiac Resynchronization Therapy Defibrillators (CRT-Ds) in patients with heart failure and narrow QRS and dyssynchrony by echocardiography does not improve the primary efficacy and may increase mortality.

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Johannes Holzmeister
2013-09-03

Original title: Cardiac-Resynchronization Therapy in Heart Failure with a Narrow QRS Complex.