ACC 2019 | SAFARI: Unexpectedly, Radial Approach Offers No Benefits In STEMI

This study was not able to show benefits in terms of mortality or bleeding when using radial vs. femoral approach in patients undergoing ST elevation myocardial Infarction.

ACC 2019 | SAFARI: sorpresivamente, el acceso radial no ofrece ventajas en el infartoThis small trial does not change things for “radialists” way past their learning curve who already feel confident with this technique. For them, there is no way back. Despite there is significant evidence in favor of this technique, there are many interventionists who still won’t switch to radial, mostly in the US. What is more, after these findings, many interventionists who still resist, might never switch to radial.

 

The SAFARI-STEMI findings, presented at the ACC 2019 Scientific Sessions, has reported that 30-day mortality for primary PCI via transfemoral approach is similar to same procedure via transradial approach.


Read also: ACC 2019 | PARTNER 3: Low Risk TAVR vs. Surgery, Fewer Events per Year.


Not only mortality and bleeding resulted similar, but also all the other secondary end points.

 

Bleeding resulted similar regardless its definition (major TIMI, minor TIMI, BARC 3 to 5, need for transfusion, etc).

 

These outcomes stand against other previously published trials, such as the RIVAL, the MATRIX, and the RIFLE-STEACS. These last two have shown lower mortality and bleeding rates and are still valid, seeing as the present study was deemed futile and therefore stopped prematurely.


Read also: ACC 2019 | TAVR in Low-Risk Patients Is Noninferior.


The message would be that many fellow interventionists believe transfemoral PCI, beyond merely outdated and obsolete, is instead borderline “mal praxis”.

 

An expert operator with vast transfemoral experience can safely continue using this approach with no concern.

 

The SAFARI-STEMI originally thought to include around 5000 patients, but after 2292 patients, gathered data failed to show differences, which resulted in its early termination.


Read also: TAVR in Low-Risk Patients with “Zero” Mortality and “Zero” Stroke.


For those who still prefer the transfemoral approach in LATAM: it is worth mentioning that 68.2% of times a percutaneous closure device was used, not a minor detail when it comes to their cost in our countries, compared to other latitudes.

 

Original title: The Safety and Efficacy of Femoral Access vs Radial Access in STEMI.

Presenter: Le May MR.


Subscribe to our weekly newsletter

Get the latest scientific articles on interventional cardiology

We are interested in your opinion. Please, leave your comments, thoughts, questions, etc., below. They will be most welcome.

More articles by this author

Coronary Artery Disease in Aortic Stenosis: CABG + SAVR vs. TAVR + PCI: Data from Spanish Centers

Multiple randomized studies have shown comparable or superior efficacy of transcatheter aortic valve replacement (TAVR) vs. coronary artery bypass graft (CABG).  However, many of...

Evolution of Small Balloon-Expandable Valves

Small aortic rings (20 mm) have posed a significant challenge for both surgery and transcatheter aortic valve implantation (TAVI) due to their association with an...

TCT 2024 | FAVOR III EUROPA

The study FAVOR III EUROPA, a randomized trial, included 2,000 patients with chronic coronary syndrome, or stabilized acute coronary syndrome, and intermediate lesions. 1,008...

TCT 2024 – ECLIPSE: Randomized Study of Orbital Atherectomy vs Conventional PCI in Severely Calcified Lesions

Coronary calcification is associated with stent under-expansion and increased risk of both early and late adverse events. Atherectomy is an essential tool for uncrossable...

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Related Articles

SOLACI Sessionsspot_img

Recent Articles

Severe Tricuspid Regurgitation: Surgical vs. Transcatheter Edge-to-Edge Repair

While highly prevalent, tricuspid regurgitation is a notably undertreated valvulopathy. Its progression has been associated with higher mortality and significant disability. According to the...

ACCESS-TAVI: Comparing Post TAVR Vascular Closure Devices

Transcatheter aortic valve replacement (TAVR) is a well-established option to treat elderly patients with severe symptomatic aortic valve stenosis. Technical advances and device development...

Endovascular Treatment of Iliofemoral Disease for the Improvement of Heart Failure with Preserved Ejection Fraction

Peripheral artery disease (PAD) is a significant risk factor in the development of difficult-to-treat conditions, such as heart failure with preserved ejection fraction (HFpEF)....