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TCT 2014.

September 13 to 17 at the Walter E. Washington Convention Center in Washington, DC. Find the best presentations of the event courtesy of SBHCI. SOLACI / SBHCI / GI2@TCT Session was held on Saturday, September 13 from 19 to 21 hours at room 143C level 1. // Read Session Program

US CoreValve: Cost effectiveness of transcatheter replacement versus surgical replacement in high-risk patients
Previous studies have shown clinical benefits, but also an increased cost to treat patients with symptomatic severe aortic stenosis receiving transcatheter valve replacement (TAVR). There is ...

CoreValve US Pivotal Trial: 2-year results of the self-expanding valve on inoperable patients
This study evaluated the safety and effectiveness of the CoreValve transcatheter valve replacement in patients with severe aortic stenosis with extreme risk for surgery.  The primary end ...

PARTNER cohort B: 5-year results of a balloon-expandable valve on inoperable patients
This study included 358 patients considered inoperable, randomized to TAVR with expandable balloon valve versus conservative treatment. The 5-year end points included all-cause mortality, cardiac ...

CLEAN-TAVI: transcatheter aortic valve replacement with cerebral protection
The stroke is a leading complication of post transcatheter aortic valve implantation increasing up to 3 times the mortality of these patients. In the works performed neuroimaging new post, TAVR ...

ISAR-CLOSURE: FemoSeal and ExoSeal versus manual compression after femoral access
Previous studies with vascular closure devices showed shorter hemostasis and less downtime post-procedure. This study compared the safety and efficacy of two vascular closure devices (FemoSeal and ...

TCT 2014 – Poster Presentation | Inspiron Registry: Safety and efficacy in a group of patients at very high risk.
TCT 2014-09-14 ...

CTO-IVUS: IVUS clinical impact in total occlusions with 2nd generation DES
While the use of intravascular ultrasound (IVUS) during coronary intervention proved useful in multiple studies, there is limited evidence in the literature regarding its use in specifically in ...

DKCRUSH-VI: FFR versus conventional angiography in true bifurcations and provisional stent
The aim of this study was to compare angioplasty guided by fractional flow reserve (FFR) versus conventional angiography in bifurcations treated with provisional stent technique for lateral ...

ABSORB 2: Results at one year of bioabsorbable platform versus Xience
This randomized, controlled, multicenter and blind study compared the second generation of bio-absorbable stent platform with the everolimus-eluting Xience . 501 patients were randomized 2: 1 ...

RIBS IV: Drug-eluting balloon versus everolimus-eluting stent on in-stent restenosis
This prospective, multicenter, randomized trial compared the paclitaxel -eluting balloon versus everolimus -eluting stent to treat patients with in-stent restenosis . 309 patients were included ...

OCT-STEMI: Primary angioplasty guided by OCT
This study included 201 patients suffering ST-segment elevation acute coronary syndrome and randomized to the use of optical coherence tomography (OCT) versus conventional angiography for the ...

OPTIMIZE: 3 months versus 12 months of dual anti-aggregation with zotarolimus-eluting stents
The current recommendation for dual anti-aggregation post-DES implantation is 12 months. However, the ideal length for specific types of stents is unclear. This study aimed to evaluate the clinical ...

DESTINY TRIAL: Stent de hastes finas com polímero eluidor de sirolimus
Pedro Lemos 2014-09-16 ...

BRIGHT: Bivalirudin versus heparin versus heparin plus tirofiban in primary angioplasty
The HORIZONS-AMI and EUROMAX studies, had already shown that bivalirudin is superior to heparin plus inhibitors IIB / IIIA glycoprotein in reducing adverse clinical events in patients suffering an ...

ISAR-TRIPLE: 6 weeks versus 6 months of clopidogrel in patients with oral anticoagulation and drug-eluting stent
There are a significant number of patients receiving drug-eluting stents and besides, require oral anticoagulation. The combination of anticoagulants, aspirin, and clopidogrel greatly increases the ...

SECURITY: 6 months versus 12 months of dual anti-aggregation using 2nd generation DES
This multicenter noninferiority design work included 1399 patients randomized to receive 6 months (n = 682) versus 1 year (n = 717) dual anti-aggregation after implantation of 2nd generation ...

TRANSLATE-ACS: One-year prasugrel versus clopidogrel after acute coronary syndrome
Platelet inhibition is critical in reducing atherothrombotic risk in the short and long term after an acute coronary syndrome, especially if the patient has received coronary angioplasty. Few data ...

VELOCITY: Peritoneal hypothermia in patients undergoing primary angioplasty
There are clinics hypothesis that systemic hypothermia (≤34.9) could reduce infarct size if set before reperfusion. Peritoneal lavage had a well-established safety profile and given the large ...

EXCITE ISR: Excimer laser versus balloon angioplasty for stent restenosis of the superficial femoral
This multicenter, prospective, randomized trial compared the Excimer laser atherectomy (Excimer Laser Atherectomy = ELA, Spectranetics, Inc.) with a balloon angioplasty in patients with in-stent ...

EVERBIO II: Bio-absorbable stent Absorb versus everolimus-eluting or biolimus stents
The new generation drug-eluting everolimus or biolimus stents have proved superior to the first generation. However, neo intimal proliferation and late thrombosis remains a problem not yet solved ...

TAVR: Study comparing cardiac magnetic resonance versus transthoracic echocardiography to assess and quantify aortic regurgitation in patients undergoing TAVI
Henrique Ribeiro 2014-09-17 ...

INOVARE VALVE: Braile prosthesis for the treatment of transapical aortic stenosis
Diego Gaia 2014-09-17 ...

I-LOVE-IT2: Drug-eluting stents with a permanent polymer versus biodegradable in the same cobalt chromium platform
There is no strong evidence in the literature that the polymer type isolated (permanent or degradable) influences clinical outcomes after angioplasty and if the time of double anti-aggregation ...

SYMPLICITY FLEX: Renal sympathetic denervation in patients with resistant hypertension
Mild refractory hypertension patients were defined as those with daytime systolic BP 135-149 and diastolic BP 90-94 mmHg in ambulatory monitoring. They were randomized to renal denervation (n = 35) ...

PRIMA: Closure of patent foramen ovale in patients with migraine with aura refractory
It is hypothesized that the presence of a right-left shunt can trigger migraine attacks. The aim of this study was to evaluate whether the closure of a patent foramen ovale may help treat patients ...

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