Original Title: Percutaneous Left Atrial Appendage Closure with the Watchman Device Long-Term Results Up to 5 Years. Reference: Wiebe J, Franke J, Lehn K et al. JACC Cardiovascular Interventions Vol. 8, NO. 15, 2015 Doi: 10.1016/j.jcin.2015.07.040 Courtesy of Dr. Agustín Vecchia. Atrial fibrillation (AF) is one of the most predominant arrhythmias and is associated to cardioembolic…
MitraClip Similar to Surgery at 5 Years
Original Title: Randomized Comparison of Percutaneous Repair and Surgery for Mitral Regurgitation. 5 – Years Results of EVEREST II. Reference: Ted Feldman et al. J Am Coll Cardiol 2015;66:2844-54 Courtesy of Dr. Carlos Fava The MitraClip at 12 months in the EVEREST II trial showed similar outcomes to that of surgery, with improved ventricular remodeling and…
Comparing Computed Tomography vs. Angiography to Assess Transfemoral Access for TAVI
Original Title: Transfemoral Access Assessment for Transcatheter Aortic Valve Replacement Evidence Based Application of Computed Tomography over Invasive Angiography. Reference: Circ Cardiovas Imaging 2015 DOI:10.1161/CIRCIMAGING.114.0011995. Courtesy of Dr. Guillermo Migliaro Transfemoral access for TAVI was introduced in 2006 and is considered first choice. Vascular complications (VCs) are important events that correlate to increased mortality. According to the…
Cost-Effectiveness of Left Atrial Appendage Closure and the New Anticoagulants vs. Warfarin in Atrial Fibrillation
Original Title: Time to Cost-Effectiveness Following Stroke Reduction Strategies in AF Warfarin vs. NOACs vs. LAA Closure. Reference: Vivek Y. Reddy et al. J Am Coll Cardiol. 2015;66(24):2728-2739. Left atrial appendage closure and the new anticoagulants (NOACs) have emerged as safe and effective alternatives to warfarin for stroke in patients with non-valvular atrial fibrillation. This analysis…
TAVI: Mobility Predicts Outcomes
Original Title: Poor Mobility Predicts Adverse Outcomes Better Than Other Frailty Indices in Patients Undergoing Transcatheter Aortic Valve Implantation. Reference: James Cockburn, et al. Catheterization and Cardiovascular Intervention 2015;86:1271-1277 Courtesy of Dr. Carlos Fava Interventional Cardiologist Favaloro Foudation – Buenos Aires There is a group of high risk patients that are also fragile, and there is…
Bleeding Events after Left Atrial Appendage Closure vs. Long Term Warfarin
Original Title: Bleeding Outcomes After Left Atrial Appendage Closure Compared With Long-Term Warfarin A Pooled, Patient-Level Analysis of the WATCHMAN Randomized Trial Experience. Reference: Matthew J. Price et al. J Am Coll Cardiol Intv. 2015. Online before print. The aim of this trial was to compare the relative risk of major bleeding after left atrial appendage closure…
Spontaneous Regression of Paravalvular Aortic Regurgitation with Self-Expanding Prosthesis
Original Title: Regression of Paravalvular Aortic Regurgitation and Remodeling of Self-Expanding Transcatheter Aortic Valve. An Observation From the CoreValve U.S. Pivotal Trial. Reference: Jae K. Oh et al. J Am Coll Cardiol Img. 2015, online first. The aim of this study was to describe the natural evolution and the clinical significance of paravalvular aortic insufficiency after…
TAVI in patients older than 90: similar outcomes to those obtained in younger patients
Original title: Comparison of Outcomes of Transcathether Aortic Valve Implantation in Patients ≥90 Years Versus <90 Years. Reference: Yigal Abramowitz, et al. Am J Cardiol 2015;116:1110-1115. More and more 90 year old patients require transcatheter aortic valve replacement (TAVI); however, its benefits have not been studied in this particular population. This study enrolled 734 patients…
Long Term Outcomes of the Transcatheter Pulmonary Valve Melody
Original title: Clinical and Hemodynamic Outcomes Up to 7 Years After Transcatheter Pulmonary Valve Replacement in the US Melody Valve Investigational Device Exemption Trial. Reference: Circulation. 2015 May 5. [Epub ahead of print]. Published studies on transcatheter pulmonary valve replacement with the Melody valve have shown good short term outcomes but there is no information of long term…
Incidence and clinical impact of post TAVI infective endocarditis
Original title: Incidence and clinical impact of infective endocarditis after transcatheter aortic valve implantation. Reference: Manuel Martínez-Sellés et al. EuroIntervention 2015;10-online publish-ahead-of-print February 2015. Prosthesis endocarditis is a complication with serious clinical consequences due to its high morbimortality. Infective endocarditis (IE) in TAVI has been described in few cases and, in cohort studies, it occurs within 0 to…
Impact of kidney function on TAVI outcome
Original title: Impact of chronic kidney disease on the outcome of transcatheter aortic valve implantation: results from the FRANCE 2 Registry. Reference: Atsushi Oguri, et al. EuroIntervention 2015;10:e1-9 Globally, 13% of patients present kidney failure, which has been associated to a worse evolution not only of TAVI outcomes but also of other cardiovascular intervention outcomes. Most studies, including…