Coronary angioplasty via radial access using 4 Fr introducer. Minimally invasive to the extreme.

Original title: Comparison of frequency of Radial Artery Oclusion Alter 4Fr Versus 6Fr Transradial Coronary intervention (from the Novel Angioplasty Using Coronary Accessor Trial). Reference: Satoshi Takesita, et al. Am J Cardiol 2014;113:1986-89)

Since Andreas Gruentzig performed the first angioplasty, technological development has improved devices and radial access becomes more common.  This procedure reduces complications, mainly bleeding. However, although is clinically not relevant, there is a chance of radial artery occlusion in between 3% and 10%. 

In this multicenter, randomized, prospective study, 160 patients who received angioplasty by radial access with Allen test (+), were included, 80 with 4 Fr introducer and 80 with 6 Fr. We excluded those who required secondary branch protection by kissing balloon, cutting balloon, rotational atherectomy or IVUS not compatible with 4 Fr. The Primary Endpoint was the occlusion of the radial artery a day after the procedure and secondary was the procedural success, MACE, vascular access complications, procedure time and contrast used. The characteristics of both groups were similar, the mean age was 68 years, most men and more than 70% of coronary lesions were single (A or B1). Three patients (4%) of group 6 Fr presented occlusion of the radial artery and none in the 4 Fr group (p = 0.08). There was no difference with respect to the secondary endpoint except for the shorter hemostasis and vascular complications related to access. 

Conclusion: 

The use of radial access with introducer and 4 Fr catheters can become a less invasive alternative in simple coronary angioplasty.

Editorial comment

The use of 4 Fr in coronary angioplasty marks an important advance in this technique, but can be used in non-complex procedures only, giving benefit especially to patients with thin gauge arteries and prone to spasm. Further technological development are needed in order to perform complex angioplasties using compatible devices with 4 Fr. 

Courtesy of Carlos Fava
Cardiólogo Intervencionista
Fundación Favaloro
Buenos Aires

Dr. Carlos Fava

More articles by this author

Is IVUS Always Necessary for Left Main Coronary Artery PCI?

Percutaneous coronary intervention (PCI) of the unprotected left main coronary artery is a highly complex procedure because of the large amount of myocardium at...

Dual-Prep Registry: Atherectomy and IVL for Severe Coronary Calcification

Severe coronary calcification remains one of the most challenging scenarios in percutaneous coronary intervention (PCI). Although rotational or orbital atherectomy and intravascular lithotripsy (IVL)...

Prehospital heparin in STEMI: A safe strategy associated with improved early reperfusion

Early reperfusion remains the main prognostic determinant in patients with ST-segment elevation myocardial infarction (STEMI). Although primary percutaneous coronary intervention (PCI) is the treatment...

Plaque Ruptures in Non-Culprit Arteries: Follow-Up With Intravascular Imaging

Plaque rupture remains one of the most important pathophysiological mechanisms in acute coronary syndromes. However, not all ruptures manifest clinically as ischemia, myocardial infarction,...

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Related Articles

SOLACI Sessionsspot_img
Jornadas Guatemala 2026

Recent Articles

UNICORN Technique to Prevent Coronary Obstruction During TAVI: Initial Results From a Multicenter Study

Coronary obstruction is an uncommon but potentially catastrophic complication of transcatheter aortic valve implantation (TAVI), particularly in valve-in-valve procedures, TAV-in-TAV interventions, or in patients...

Supera vs. Eluvia at 3 Years in Severely Calcified Femoropopliteal Lesions

Severe calcification remains one of the main predictors of restenosis and the need for repeat revascularization following endovascular treatment of femoropopliteal disease. In this...

Is IVUS Always Necessary for Left Main Coronary Artery PCI?

Percutaneous coronary intervention (PCI) of the unprotected left main coronary artery is a highly complex procedure because of the large amount of myocardium at...