The aim of this study was to test whether perioperative treatment with rosuvastatin 20 mg could prevent the incidence of postoperative atrial fibrillation and reduce myocardial damage in patients undergoing cardiac surgery. The data showed that rosuvastatin was not effective in preventing the occurrence of atrial fibrillation or reduce myocardial damage measured by troponin.  Barbara…

This study included 1504 patients with atrial fibrillation and indication for elective electrical cardioversion who were randomized to rivaroxaban (n = 1002) versus Marevan (n = 502).  The safety end point, major bleeding occurred in 0.61% of rivaroxaban group versus 0.8% of Marevan (95% IC 0.21-2.67, p = NS). The rate of stroke, embolic events,…

Statins may help stabilize the atherosclerotic plaque in acute myocardial infarction. 103 patients who underwent primary angioplasty followed by coronary intravascular ultrasound (IVUS) in the culprit artery and not culprit of infarction were included. Patients received 20 mg of rosuvastatin for two weeks and then 40 mg for 13 months ending up with a new…

Tuberculous pericarditis is associated with high morbidity and mortality. This study included 1400 patients with definite or probable tuberculous pericarditis to receive prednisolone or placebo for 6 weeks. Two-thirds of patients had concomitant HIV infection. The primary end point was a composite of death, tamponade, or constrictive pericarditis. No significant differences between those who received…