Original title: Incidence and clinical impact of infective endocarditis after transcatheter aortic valve implantation. Reference: Manuel Martínez-Sellés et al. EuroIntervention 2015;10-online publish-ahead-of-print February 2015. Prosthesis endocarditis is a complication with serious clinical consequences due to its high morbimortality. Infective endocarditis (IE) in TAVI has been described in few cases and, in cohort studies, it occurs within 0 to…
Paclitaxel coated balloon catheter vs. DES for DES instent restenosis
Original title: Paclitaxel – coated balloon catheter compared with drug- eluting stent for drug-eluting stent restenosis in routine clinical practice. Reference: SeijiHabara et al.EuroIntervention 2015; 10-online publish-ahead-of-printFebruary 2015. The paclitaxel coated balloon catheter (PCB) is not inferior to DES for the treatment of instent restenosis (IRS). The aim of this study is to compare the efficacy of the…
Double Anti platelet aggregation would be sufficient for six months after angioplasty in patients with stable coronary disease NSTSEACS.
Original title: 6- Versus 24-Month Dual Antiplatelet Therapy After Implantation of Drug. Reference: Eluting Stents in Patients Nonresistant to Aspirin The Randomized, Multicenter ITALIC Trial. JACC.VOL. 65, NO. 8, 2015 Current recommendations on dual antiplatelet therapy (DAPT) are under review, particularly in acute coronary events due largely to the advent of second-generation stents. This work studied the hypothesis…
IVUS plaque regression with high doses of statins
Original title: Effect of high-intensity statin therapy on atherosclerosis in non-infarct-related coronary arteries (IBIS-4): a serial intravascular ultrasonography study. Reference: Räber L et al. Eur Heart J. 2015 Feb 21;36(8):490-500. The long-term effect of intensive statin therapy on coronary atherosclerosis in patients admitted pursuing an ST segment elevation myocardial infarction is unknown. The aim of this study was…
Partial occlusion of coronary sinus reduces refractory angina
Original title: Efficacy of a Device to Narrow the Coronary Sinus in Refractory Angina. Reference: Verheye S et al. N Engl J Med 2015 Feb 5;372(6):519-27. The number of patients with severe diffuse coronary artery disease who are not candidates for revascularization is growing in Western countries, generating multiple procedures and increasing healthcare expenditure. New and unconventional solutions…
Zotarolimus eluting stent with one month of dual antiplatelet therapy
Original title: Zotarolimus-Eluting Versus Bare-Metal Stents in Uncertain Drug-Eluting Stent Candidates. Reference: Marco Valgimigli et al. J Am Coll Cardiol. 2015;65(8):805-815. The use of drug eluting stents (DES) in patients at high risk of bleeding or thrombosis has not been studied prospectively. Data on patients at high risk of bleeding and low restenosis are limited. This study compared…
Invasive evaluation of patients with angina in the absence of coronary lesions
Original title: Invasive Evaluation of Patients with Angina in the Absence of Obstructive Coronary Artery Disease. Reference: Bong-Ki Lee et al.Circulation published online before print February 20, 2015. More than 20% of patients presenting to the cath lab with angina symptoms have no angiographic evidence of coronary artery disease (CAD). Despite a “normal” angiogram, these patients have persistent…
The MGuard stent shows a trend toward reduced mortality in PCI
Original title: Mesh-Covered Embolic Protection Stent Implantation in ST-Segment–Elevation Myocardial Infarction. Final 1-Year Clinical and Angiographic Results From the MGUARD for Acute ST Elevation Reperfusion Trial. Reference: DariuszDudek et al. CircCardiovascInterv. 2015 Feb;8(2). The MGuard is a micronet mesh-covered stent designed to reduce distal embolization in the context of ST elevation myocardial infarction. In the MASTER study…
The poor prognosis of critical limb ischemia related to sub treatment
Original title: Peripheral arterial disease and critical limb ischaemia: still poor outcomes and lack of guideline adherence. Reference: Reinecke H et al. Eur Heart J. 2015; Epub ahead of print. This work included 41882 patients retrospectively from health insurance in Germany admitted with diagnosis of peripheral vascular disease between 2009 and 2011 and followed until 2013. Patients…
Impact of kidney function on TAVI outcome
Original title: Impact of chronic kidney disease on the outcome of transcatheter aortic valve implantation: results from the FRANCE 2 Registry. Reference: Atsushi Oguri, et al. EuroIntervention 2015;10:e1-9 Globally, 13% of patients present kidney failure, which has been associated to a worse evolution not only of TAVI outcomes but also of other cardiovascular intervention outcomes. Most studies, including…