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Pharmacology

TCT 2025 | STORM-PE: Mechanical Thrombectomy with Penumbra Lightning+AC vs. Anticoagulation Alone in Intermediate-High Risk PE

Intermediate-high risk pulmonary embolism (PE) remains a therapeutic challenge. Anticoagulation is still the standard treatment, albeit with...

HELP-PCI: A Fleeting Advantage of Early Heparin in ST-Elevation Myocardial Infarction?

In ST-elevation myocardial infarction (STEMI), immediate reperfusion through primary percutaneous coronary intervention (pPCI) remains the treatment of...

ESC 2025 | HI-PRO: Extended Apixaban for Recurrence Prevention in Provoked DVT/PE

Patients with provoked venous thromboembolism (VTE) usually discontinue anticoagulation after 3 to 6 months. However, in the...

ESC 2025 | BETAMI-DANBLOCK: Randomized Discontinuation of Beta-Blockers after MI

The routine use of beta-blockers after acute myocardial infarction (AMI) has been a historical recommendation based on...

ESC 2025 | DIGIT-HF: Digitoxin in Heart Failure with Reduced Ejection Fraction

Heart failure with reduced ejection fraction (HFrEF) continues to represent a clinical challenge despite advances in pharmacological...

ESC 2025 | What Should We Do With Beta-Blockers Post-MI in Patients With Preserved LVEF?

The evidence supporting the use of beta-blockers after myocardial infarction (MI) is strong in patients with ventricular...

ESC 2025 | DUAL-ACS: Duration of Dual Antiplatelet Therapy in Acute Coronary Syndromes

The DUAL-ACS trial, a randomized multicenter study, was designed to evaluate whether a strategy of P2Y12 inhibitor...

ESC 2025 | SWEDEPAD 1 and 2: Paclitaxel-Coated Devices in Peripheral Artery Disease

In patients with peripheral artery disease, “improving” prognosis means relieving walking pain, increasing walking distance, preventing amputations,...