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Pharmacology

Aspirin, Clopidogrel and Warfarin. Is it safe or is a triple scheme necessary?

Original title: Use of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous...

Improved efficacy and also increased bleeding with Rivaroxaban in Acute Myocardial Infarction

Original title: Rivaroxaban in Patients Stabilized After a ST-Segment Elevation Myocardial Infarction. Results From the ATLAS ACS-2–TIMI-51 Trial....

Bivalirudin reduces bleeding complications in carotid angioplasty

Original title: Hemorrhagic and ischemic outcomes after bivalirudin versus unfractionated heparin during carotid artery stenting: A propensity score...

Endovascular Therapy in Acute Stroke Still Being Discussed

Original title: Mechanical Recanalization with Flow Restoration in Acute Ischemic Stroke. The Mechanical Recanalization with Flow Restoration in...

Prasugrel is not as effective as Ticagrelor in acute myocardial infarction. 

Original title: Comparison of Prasugrel and Ticagrelor loading doses in STEMI patients: The Rapid Activity of Platelet Inhibitor...

Cangrelor: more effective than clopidogrel without increasing bleeding 

Original title: Effect of Platelet Inhibition with Cangrelor during PCI on Ischemic Events. CHAMPION PHOENIX. Reference: Deepak L. Bhatt et...

Appendage trans-catheter closure is equivalent to anticoagulation in fibrillated patients.

Original title: Percutaneous Left Atrial Appendage Closure for Stroke Prophylaxis in Patients With Atrial Fibrillation: 2.3-Year Follow-up of...

Endovascular therapy after t-PA: no additional benefit for patients with acute stroke

Original title: Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke. Interventional Management of Stroke (IMS) III. Reference: Joseph...