Data from a great Australian registry of nearly 250,000 people with a 5-year follow-up, presented at the European Society of Cardiology (ESC) Congress 2019 in Paris and simultaneously published in J Am Coll Cardiol, suggest that mortality due to severe aortic stenosis is similar to that due to moderate aortic stenosis. These data warn us…
ESC 2019 | Pure: Body Mass Index Shows Low Correlation with Cardiovascular Events
This population study has found all-cause mortality is lower the lower body mass index (BMI) is, but lower BMI is not necessarily better. In fact, the lowest mortality in this global analysis was found in patients with medium BMI. Other anthropometric measurements such as hip/waist ratio and strength/weight ratio are better predictors of events and…
New FDA Updates on Paclitaxel Device Outcomes
A new FDA letter confirms late mortality signal with paclitaxel eluting stents and paclitaxel coated balloons in peripheral territory. Even though this recently published letter confirms data, there are no new recommendations on the use of these devices. After careful consideration of their own analyzis outcomes and a 2-day discussion of an advisory panel especially…
Mortality and Paclitaxel Devices, Data Are Aligning
5 years ago, several prospective randomized studies confirmed paclitaxel coated balloons were safe and effective in femoropopliteal territory. However, a recently published meta-analysis of heterogeneous studies including both paclitaxel coated balloons and drug eluting stents has linked these devices to mortality. In addition, higher doses were associated to higher mortality, both at 2 and 5…
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