Tag Archives: statins

indicación de tratamiento con estatinas

Could Statins Do More than Lower Cholesterol in COVID-19 Patients?

Could Statins Do More than Lower Cholesterol in COVID-19 Patients?

A history of acute myocardial Infarction, cardiac failure or hyperlipidemia has been associated with increased mortality of COVID-19. Observational studies have suggested statins might reduce death risk from COVID-19, in addition to lowering cholesterol.  Statins have anti-inflammatory and antithrombotic effects that could play a role in the course of the infection.  Other studies have arrived

Pacientes que no siguen nuestro consejo y sorpresivamente tienen menos eventos

Polypharmacy in Older Adults Elderly: What Medication to Discontinue

Polypharmacy is certainly a problem in the elderly population. Forgetfulness, and drug and dose confusion can lead to multiple problems; in addition, over time, cognitive deterioration will make complicated drug management schemes even more difficult for patients to handle.  Aware of this problem, physicians often try to simplify schemes by discontinuing drugs, but what should

AHA 2020 | POLYPILL: Una sola pastilla más aspirina para tratar todo

AHA 2020 | POLYPILL: One Pill Plus Aspirin to Treat Everything

Using only one compressed tablet or pill with a fixed combination of statins, angiotensin-converting enzyme inhibitors, beta-blockers, and diuretics significantly lowered cardiovascular risk in a large population without previous events (primary prevention). However, it presented an intermediate risk of cardiovascular disease onset. The TIPS-3 (The International Polycap Study 3) study had a 2-by-2-by-2 factorial design,

AHA 2020 | Statins: Confirmed Benefits for the Elderly

Elderly patients (>70) with high cholesterol levels have been systematically excluded from randomized studies on statins, despite their higher risk of cardiovascular events. Presented at AHA 2020 Scientific Sessions and published simultaneously in the Lancet, along comes this primary prevention study including patients between 70 and 100 years of age.  The use of therapies to

Seguridad de los balones con paclitaxel en enfermedad vascular periférica

Peripheral Artery Disease: Underestimated and Undertreated

Compared against coronary artery disease (CAD) or cerebrovascular disease patients, peripheral artery disease (PAD) patients have lower chances of receiving medication proved to be clinically effective such as statins (despite running the same risk, perhaps even higher risk).  The message is we should be more active both in finding risk factors in PAD patients, and

ACC 2020 Virtual | Las estatinas también podrían proteger la cardiotoxicidad de la quimioterapia

Virtual ACC 2020 | Statins Could Also Protect Against Chemotherapy Cardiotoxicity

This retrospective study has shown a reduction in hospitalization for cardiac failure in patients who were already using statins receiving anthracycline and trastuzumab in the context of breast cancer.   The study was to be presented during the ACC 2020 scientific sessions together with the World Congress of Cardiology. However, it had to be called off

Nuevas guías de dislipemia

New European Guidelines for Dyslipidemia Management: What is New?

Reading clinical practice guidelines, except for specific consultation, is usually tedious. These guidelines are nor meant to be read as a textbook, or at least this is what most readers believe.  But it looks like this reader’s perception has finally been acknowledged, hence “table 3” in the new European dyslipidemia guidelines, where the new recommendations,

Pretratamiento con estatinas para prevenir eventos peri angioplastia carotidea

Secondary Prevention: A Responsibility We Should Not Delegate

After coronary angioplasty, the use of drugs whose efficacy for the reduction of major events has been proven declines over time, which is associated with worse patient prognosis. Sometimes, without meaning to, we convey to patients the idea that, once the stent has been implanted, the artery is “cured” or that the only potential future

Treat Stroke to Target: terapia agresiva con estatinas post stroke

AHA 2019 | Treat Stroke to Target: Post-Stroke Aggressive Therapy with Statins

Indicating statins to reach more aggressive LDL goals in patients that have suffered transient ischemic attack or ischemic stroke driven by atherosclerosis significantly reduces major cardiovascular events according to this study presented in the AHA 2019 scientific sessions simultaneously published in NEJM. The study was prematurely ended because of lack of funding, but its outcomes