Tag Archives: statins

ticagrelor diabeticos

The Elderly and Polypharmacy: What to Discontinue

The Elderly and Polypharmacy: What to Discontinue

We often receive elderly poly-medicated patients (with more than 10 different drugs) who ask us to reassess these prescriptions and, if possible, discontinue some drugs. The reasons are many: they forget to take it, mix up intakes or drugs, and of course, most often find it expensive.  Statins are one of the most expensive drugs

Pretratamiento con estatinas para prevenir eventos peri angioplastia carotidea

Secondary Prevention: A Responsibility We Should Not Delegate

After coronary angioplasty, the use of drugs whose efficacy for the reduction of major events has been proven declines over time, which is associated with worse patient prognosis. Sometimes, without meaning to, we convey to patients the idea that, once the stent has been implanted, the artery is “cured” or that the only potential future

Treat Stroke to Target: terapia agresiva con estatinas post stroke

AHA 2019 | Treat Stroke to Target: Post-Stroke Aggressive Therapy with Statins

Indicating statins to reach more aggressive LDL goals in patients that have suffered transient ischemic attack or ischemic stroke driven by atherosclerosis significantly reduces major cardiovascular events according to this study presented in the AHA 2019 scientific sessions simultaneously published in NEJM. The study was prematurely ended because of lack of funding, but its outcomes

Las nuevas guías de dislipemia apoyan la terapia sin estatinas y la búsqueda de calcio coronario

AHA 2018 | New Dyslipidemia Guidelines Support Non-Statin Therapy and Coronary Artery Calcium Screening

While the guidelines do not recommend a specific treatment target, they suggest additional therapy in high-risk patients with LDL 70 mg/dL or higher. These new guidelines from the American College of Cardiology (ACC) and the American Heart Association (AHA) start recommending ezetimibe or PCSK9 inhibition in select high-risk patients and proposing noninvasive coronary artery calcium screening

Statin Pre-Treatment for the Prevention of Peri-Procedural Events in Carotid Artery Stenting

What is the effect of statins on amputations, and survival in peripheral vascular disease?

The prevalence of peripheral arterial disease is between 15% and 20% of patients older than 65 years and its severity is greatly underestimated. In fact, annual mortality is higher in patients with peripheral arterial disease (8.2%) than in those after acute myocardial infarction (6.3%). Despite the above, medical advice and efforts to modify risk factors

Nuevas guías de dislipemia

Strict LDL Monitoring Helps Reduce Plaque Volume

The aim of this study was to explore the relationship between temporal changes in coronary plaque volume and the intensity of lipid lowering treatments using coronary computed tomography (CTA).   Coronary computed tomography has acceptable accuracy in terms of quantitative measurement on plaque volume, enough to identify changes in volume according to LDL levels.  

HOPE 3: Reducing LDL Improves Prognosis in Intermediate Risk Patients

In a large cohort of intermediate risk patients with no known CAD, treatment with low doses of statins in addition to an angiotensin receptor blocker and a diuretic, reduce the risk of cardiovascular events, compared to placebo. These are the main findings of the HOPE 3 trial (Heart Outcomes Prevention Evaluation) that randomized 12705 patients,

JUPITER Subanalysis: Reduction of LDL Determines Clinical Impact of Rosuvastatin Therapy

Original Title: Cholesterol treatment targets and clinical outcomes: a JUPITER trial update. Presenter: Paul Ridker. The lower the LDL cholesterol levels, the less adverse cardiovascular events in men and women initially healthy, according to an analysis of the JUPITER trial. Findings could help inform about the optimal LDL goals in primary prevention. To explore the